Beryllium granulomatosis complicated by tuberculosis; report of a case treated with ACTH.

Abstract

Case Reports1 February 1953BERYLLIUM GRANULOMATOSIS COMPLICATED BY TUBERCULOSIS: REPORT OF A CASE TREATED WITH ACTHR. LOWRY DOBSON, JOHN C. WEAVER, LEON LEWIS, F.A.C.P.R. LOWRY DOBSONSearch for more papers by this author, JOHN C. WEAVERSearch for more papers by this author, LEON LEWIS, F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-38-2-312 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAlthough beryllium and its compounds have been recognized as serious industrial hazards for only a decade, the available information concerning toxic manifestations in man and experimental animals has already become extensive. The first patient with a diffuse pulmonary granulomatosis later shown to have been due to beryllium was observed during 1941 at the Essex Sanatorium in Middleton, Massachusetts.1Following recognition of the clinical entity, many controversies arose concerning the rôle of beryllium as an etiologic agent as opposed to that of the electronegative ions of beryllium salts. The experimental investigation of poisoning due to this metal has been characterized by...Bibliography1. Shipman PL: History of the beryllium problem, in Pneumoconiosis, 1950, Paul B. Hoeber, Inc., New York, pp. 3-10. Google Scholar2. HyslopPalmesAlfordMonacoFairhall FEDWCARLT: The toxicity of beryllium, National Institute of Health Bull. No. 181, U. S. Pub. Health Service, Washington, D. C., 1943. Google Scholar3. SpragueLabellePettengillStokinger GFCWAGHE: Initial studies of the toxicity of inhaled beryllium sulfate dust and beryllium metal fume, in Pneumoconiosis, 1950, Paul B. Hoeber, Inc., New York, pp. 326-352. Google Scholar4. Van OrdstrandHughesDe NardiCarmody HSRJMMG: Beryllium poisoning, J. A. M. A. 129: 1084-1090, 1945. CrossrefMedlineGoogle Scholar5. HardyTabershaw HLIR: Delayed chemical pneumonitis occurring in workers exposed to beryllium compounds, J. Indust. Hyg. and Toxicol. 28: 197-211, 1946. MedlineGoogle Scholar6. Gardner LU: Generalized pulmonary granulomatosis occurring among workers believed to be exposed to beryllium or its compounds, Trans. Eleventh Ann. Meeting of Indust. Hyg. Fdt. of Amer., Inc., Bull. No. 8, pp. 89-94, Nov. 7, 1946. Google Scholar7. MartlandBrodlkinMartland HSHAHS: Occupational beryllium poisoning in New Jersey, J. M. Soc. New Jersey 45: 5-15, 1948. MedlineGoogle Scholar8. De NardiVan OrdstrandCarmody JMHSMG: Chronic pulmonary granulomatosis, Am. J. Med. 7: 345-355, 1949. CrossrefMedlineGoogle Scholar9. Dutra FR: The pneumonitis and granulomatosis peculiar to beryllium workers, Am. J. Path. 24: 1137-1165, 1948. MedlineGoogle Scholar10. Chesner C: Chronic pulmonary granulomatosis in residents of a community near a beryllium plant: three autopsied cases, Ann. Int. Med. 32: 1028-1048, 1950. LinkGoogle Scholar11. RobertsonSiriJones JSWEHB: Lung ventilation patterns determined by analysis of nitrogen elimination rates; use of the mass spectrometer as a continuous gas analyser, J. Clin. Investigation 29: 577-590, 1950. CrossrefMedlineGoogle Scholar12. Steadman LT: Personal communication. Google Scholar13. EisenbudWantaDustanSteadmanHarrisWolf MRCCLTWBBS: Nonoccupational berylliosis, J. Indust. Hyg. and Toxicol. 31: 282-294, 1949. MedlineGoogle Scholar14. Reynolds PW: Beryllium disease from the ceramic industry, Arch. Ind. Hyg. Occ. Med. 3: 575-578, 1951. Google Scholar15. SternerEisenbud JHM: The epidemiology of beryllium intoxication, Indust. Health Monthly 11: 104-105, 1951. MedlineGoogle Scholar16. KennedyParePumpBeckJohnsonEpsteinVenningBrowne BJJAKKJCLGNBEHJS: Effect of adrenocorticotrophic hormone (ACTH) on beryllium granulomatosis and silicosis, Am. J. Med. 10: 134-155, 1951. CrossrefMedlineGoogle Scholar17. HardyBartterJaffin HLFCAE: Metabolic study of a case of chronic beryllium poisoning treated with ACTH, Arch. Ind. Hyg. Occ. Med. 3: 579-582, 1951. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Berkeley, California*Received for publication December 12, 1951.From the Radiation Laboratory and the Donner Laboratory of Medical Physics, University of California, Berkeley.†Industrial Health and Hygiene Associates, Berkeley, California. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byChronic beryllium diseaseZur normalen und pathologischen Histologie hautnaher LymphknotenDas adrenocorticotrope Hormon (ACTH), die HormonederNebenniere(Cortison,Adrenalin) das Insulin, sowie die Hormone der Schilddrüse und NebenschilddrüseDie Pneumonien 1 February 1953Volume 38, Issue 2Page: 312-325KeywordsAdrenocorticotropic hormoneHygienePrevention, policy, and public healthResearch laboratoriesSalts ePublished: 1 December 2008 Issue Published: 1 February 1953 PDF downloadLoading ...