Abstract
Benzodiazepines, like other sedative-hypnotics, can induce tolerance and physical dependence. This chapter reviews three types of physical dependence that can occur with benzodiazepines:a high-dose dependency of the barbiturate type, a low-dose dependency that may occur with therapeutic doses, and dependency that may occur in the neonate from placental or breast-milk transfer of a benzodiazepine.
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