Abstract
Benign lymphoid hyperplasia (BLH) of the tongue is a rare benign lymphoproliferative lesion that, histopathologically, resembles a lymphoma. An 8-year-old female presented with a firm, painless, non-ulcerated, and slow-growing swelling on the ventral surface of the tongue. The medical history included a liver transplant performed at 10 months of age and current use of immunosuppression therapy. An excisional biopsy was performed, and the microscopic examination showed multiple germinal centers with a rim of small mature lymphocytes, together with a mixed, mainly mononuclear, infiltrate. Although BLH must be distinguished from a neoplastic lymphoid proliferation, primarily follicular lymphoma, the histological features at the present case were those of a typical BLH, causing no difficulty in the diagnosis and requiring no further investigation. During follow-up, the patient showed no signs of recurrence.
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