Abstract
2. Smaller than expected bladder capacity are desmopressin resistant because the likely etiology in these children is not overproduction of urine. Hence the response to desmopressin is likely to be poor. Nocturnal polyuria is now described in some children with enuresis who respond to desmopressin. Here the overnight urine output is >130 % of expected bladder capacity. Children with smaller than expected bladder capacity do better with anticholinergics. However, in case we can document nocturnal polyuria as well as a reduced bladder capacity the two modalities can be used with synergistic effect [3]. I hope we have been able to satisfy the queries raised.
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