Abstract
Bayés's syndrome is a clinical entity based on the association between advanced interatrial block and the development of supraventricular tachyarrhythmia, being atrial fibrillation (AF) the most frequent. This association was discovered by Prof. Antoni Bayés de Luna in the '80s. Further studies by other groups found a strong relationship between Bayés's syndrome and thromboembolic phenomena, being stroke the most serious. Moreover, patients with this syndrome have an increased incidence of cognitive impairment and dementia. This observation triggered the question about whether the use of anticoagulation therapy prior to the documentation of AF could prevent A-IAB associated thromboembolic events. There are ongoing studies in different phases of development aiming to compare the efficacy of anticoagulation in patients with A-IAB with no prior documentation of AF. The outcomes of these studies will allow determining the efficacy of this early therapeutic intervention, and help deciding the role of anticoagulation in patients with A-IAB and no demonstrated AF.
Highlights
E l síndrome de Bayés se define como una entidad clínica que asocia la presencia de bloqueo interauricular avanzado (BIA-A), con el desarrollo de taquiarritmias supraventriculares (TSV), entre las cuales la fibrilación auricular (FA) y el aleteo auricular son las más frecuentes (1 – 5)
La fibrosis es el sello del remodelado auricular (2, 5, 10), y se asocia a dilatación bicameral, deformación esférica, reducción de la función atrial e, incluso, promueve el desarrollo de FA mediante un círculo vicioso (2, 5, 10)
Análisis de regresión logística múltiple demostraron que la edad (OR, 1,061; 95% CI: 1,012 – 1,113; p=0,014), la escala CHA2DS2-VASc (OR, 1,758; 95% CI: 1,045 – 2,956; p=0,034), la hipertrofia ventricular izquierda (OR, 3,062; 95% CI: 1,161 – 8,076; p=0,024) y la presencia de BIA (OR, 5,959; 95% CI: 2,269 – 15,653; p
Summary
Iominia,*; Manuel Martínez-Sellés b, c, d; Roberto Elosua b, e, f; Antoni Bayés-de-Luna f; Adrián Baranchuk g. Filiación de los autores a Estudiante de Medicina, Facultad de Medicina, Universidad de Buenos Aires (UBA), UDH Hospital Dr Prof. B Centro de Investigación en Red de Enfermedades Cardiovasculares (CIBERCV), España c Hospital General Universitario Gregorio Marañón, Madrid, España d Universidad Europea de Madrid y Universidad Complutense de Madrid, España e Facultad de Medicina, Universidad de Vic-Universidad Central de Catalunya, Vic, Barcelona, España f Fundación Investigación Cardiovascular, Programa Cardiovascular-ICCC, Institut de Recerca del Hospital de la Santa Creu I Sant Pau, IIB-Sant Pau, Barcelona, España g Division of cardiology, Kingston Health Science Center, Kingston, Ontario, Canada. Conflictos de interés Los autores declaran no tener ningún conflicto de interés
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