Abstract
Hemodialysis (HD) is primarily a diffusion-based transfer of small solutes. Diffusion is dependent on Fick's law. Convective removal, used mainly for removal of excess plasma water by ultrafiltration, also removes larger molecular-weight solutes by the process of solvent drag. A number of physicochemical factors operative on the blood and the dialysate side impact solute and water removal during HD. A comprehensive yet brief discussion of these 2 basic processes operative in HD is presented in this article.
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