Abstract
Advances in DNA sequencing have resulted in instruments of remarkable performance, including extraordinary base read rates, and enormous sequencing depths. Sample throughput, nevertheless, remains slow, a situation that could be alleviated through sample multiplexing, with the incorporation of DNA barcodes serving to identify the different samples. Given the existence of finite sequencing error rates, reported is the design from BCH codes of DNA barcodes that provide guaranteed correction of errors within these barcodes.
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