Abstract
The authors picked up eight particular cases from a series of so-called Banti's syndrome which they had experienced at their surgical department. Although these cases had most of clinical manifestations of this syndrome, they were con-trasted with typical cases because of their normal portal pressure. Histologically, spleens of these cases showed pulp hyperplasia of various grades but, unlike in typical cases of this syndrome, no evidence of sinus hyperplasia. Besides, changes in lymph follicles of spleens of these cases included increase in their population, appearance of a germinal center and hemorrhage in perifollicular areas. This paper describes the details of these findings and presents the authors' view that these eight cases represent an incipient phase of Banti's syndrome. Discussions are also made in this paper on the relation between Banti's syndrome in its early phase and so-called primary hypersplenism.
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