Abstract

Part I: Isolation of Bacteriophages 1. Isolation of Bacteriophages for Fastidious Bacteria Shigenobu Matsuzaki, Jumpei Uchiyama, Iyo Takemura-Uchiyama, Takako Ujihara, and Masanori Daibata 2. Isolation of Bacteriophages of the Anaerobic Bacteria Bacteroides Cristina Garcia-Aljaro, Maite Muniesa, and Juan Jofre 3. Isolation of Bacteriophages for Clinically Relevant Bacteria Sanna Sillankorva Part II: Characterization of Bacteriophages 4. In Vitro Activity against Planktonic and Biofilm Populations Assessed by Flow Cytometry Luis Melo, Diana Priscila Pires, and Joana Azeredo 5. Observation of Bacteriophage Ultrastructure by Cryo-electron Microscopy Ana Cuervo and Jose L. Carrascosa 6. Bacteriophage Taxonomy: an Evolving Discipline Igor Tolstoy, Andrew M. Kropinski, and J. Rodney Brister Part III: Bacteriophage Selection and Cocktail Formulation 7. Determination of the Bacteriophage Host Range - Culture Based Approach Andrey V. Letarov, and Eugene E. Kulikov 8. Recovery and Characterization of Bacteria Resisting Infection by Lytic Bacteriophage Libera Latino and Christine Pourcel 9. Guidelines to Compose an Ideal Bacteriophage Cocktail Maia Merabishvili, Jean-Paul Pirnay, and Daniel De Vos Part IV: Biodistribution, Host Interaction and Clinical Application 10. Interaction of Bacteriophages with Mammalian Cells Zuzanna Kazmierczak and Krystyna Dabrowska 11. In Vivo Bacteriophage Biodistribution Nicolas Dufour, Raphaelle Delattre, and Laurent Debarbieux 12. Interaction of Bacteriophages with the Immune System: Induction of Bacteriophage-specific Antibodies Krystyna Dabrowska & nbsp 13. Bacteriophage Treatment of Infected Diabetic Foot Ulcers Vera V. Morozova, Yulia N. Kozlova, Denis A. Ganichev, and Nina V. Tikunova 14. Compassionate Use of Bacteriophage Therapy for Foot Ulcer Treatment as an Effective Step for Moving Toward Clinical Trials Randolph Fisha, Elizabeth Kutter, Gordon Wheat, Bob Blasdel, Mzia Kutateladze, and Sarah Kuhl Part V: Production, Purification and Bacteriophage Storage 15. Bacteriophage Production in Bioreactors Maryam Agboluaje and Dominic Sauvage 16. Computational Modelling of Bacteriophage Production for Process Optimization Konrad Krysiak-Baltyn and Sally L. Gras 17. Methods for Bacteriophage Preservation Malgorzata B. Lobocka, Aleksandra Glowacka, and Piotr Golec Part VI: Safety and Regulation 18. Bacteriophage Production in Compliance with Regulatory Requirements Jean-Paul Pirnay, Maia Merabishvili, Hilde Van Raemdonck, Daniel De Vos, and Gilbert Verbeken 19. Guidelines for Bacteriophage Product Certification Alan Fauconnier Part VII: New Phage Therapy Approaches 20. Nano/micro Formulations for Bacteriophage Delivery Pilar Cortes, Mary Cano-Sarabia, Joan Colom, Jennifer Otero, Daniel Maspoch, and Montserrat Llagostera 21. Synthetic Biology to Engineer Bacteriophage Genomes Ana Rita Costa, Catarina Milho, Joana Azeredo, and Diana Priscila Pires

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