Abstract

BackgroundBacteria are the major contributor of ocular infections worldwide. Ocular infections, if left untreated, can damage the structures of the eye with possible blindness and visual impairments. This work was aimed to review the bacterial profile of ocular infections.MethodsLiterature search was made in different electronic databases; the review was systematically made to get concrete findings.ResultsAs far as this review, Staphylococcus aureus, Coagulase negative Staphylococci, Streptococcus pneumoniae and Pseudomonas aeruginosa are the leading isolates in ocular infections. Frequent pathogens of the respective clinical diagnose include Staphylococci, Streptococcus pyogenes and Pseudomonas aeruginosa in blepharitis; Staphylococci, Streptococus pneumoniae, Pseudomonas aeruginosa, Klebsiella pneumoniae and Escherichia coli in Conjunctivitis; Staphylococci, P. aeruginosa and E. coli in dacryocystitis; Coagulase negative Staphylococci, Pseudomonas aeruginosa and Staphylococcus aureus in keratitis; Streptococcus viridians, Streptococcus pneumoniae and Coagulase negative Staphylococci in endophthalmitis diagnoses. Endogenous endophthalmitis is associated with Klebsiella pneumoniae whereas Coagulase negative Staphylococci and Bacillus spp. are common causes of post-operative and post-traumatic endophthalmitis. However, the predominant pathogens may not be exactly same in all areas of the world, in the United States for instance, Staphylococcus aureus, Streptococcus pneumoniae and Haemophilus influenzae are the major causes of conjunctivitis.ConclusionGram positive bacteria are the major contributor of bacterial ocular infections. The distribution and proportion of bacterial isolates among clinical diagnoses varied but without exclusive anatomical restriction. To mitigate the burden of bacterial ocular infections, physicians should regard on risk reduction and comply with etiologic approach of diagnosis.

Highlights

  • Bacteria are the major contributor of ocular infections worldwide

  • Bacteria are generally associated with many types of ocular infections such as conjunctivitis, keratitis, endophthalmitis, blepharitis, orbital cellulitis and dacryocystitis manifestations [4]

  • Studies published until 2016 and emphasizing on external and internal ocular infections were subjected to systematic review and those that are close to the review objectives were included from different parts of the world to get concrete findings (76 out of 145); articles written and published in English language, emphasizing on any of the external-ocular infections and internal-ocular infections were included in the study

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Summary

Introduction

If left untreated, can damage the structures of the eye with possible blindness and visual impairments. This work was aimed to review the bacterial profile of ocular infections. Bacteria are the major contributor of ocular infections worldwide. Bacteria are generally associated with many types of ocular infections such as conjunctivitis, keratitis, endophthalmitis, blepharitis, orbital cellulitis and dacryocystitis manifestations [4]. Conjunctivitis, inflammation of the mucosa of conjunctiva, is the most frequent ocular case with noticeable. Blepharitis which is an inflammation of the eyelid can cause loss of eye lash [9]. The most serious eye infection is the leading cause of corneal blindness. The disease can progress to endophthalmitis if not diagnosed early [11,12,13]

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