Abstract

IV baclofen was used to treat refractory cervical muscle spasm/pain associated with migraines/daily headaches in an outpatient headache clinic. IV baclofen is not commercially available in the USA. A sterile preparation of baclofen (2.5mg/ml, pH 6.6) was made with a compounding pharmacist, and studied to reduce neck pain/spasm accompanied by refractory migraine headaches. 63 patients were treated in the clinic with pulse oximetry monitoring. 5-10 mg of IV baclofen given at intervals of 10-15 minutes with rating of muscle pain/spasm and headache/migraine every 15 minutes.

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