B-59 | Cardiovascular Outcomes and Racial Trends of Transcatheter Aortic Valve Replacement Among Octogenarians With Kidney Disease: A Subgroup Analysis

Abstract

Limited data is available regarding in-hospital outcomes of TAVR in the octogenarian population with CKD stage. We used the National Inpatient Sample (NIS) database to compare CKD stage I-III (CKD-LG) and CKD stage IV-V (CKD-HG) among octogenarians. We included a total of 89,090 octogenarian patients with CKD (TAVR CKD-LG n= 69,105; TAVR CKD-HG n= 19,985). The median age in TAVR CKD-LG and TAVR CKD-HG were 85 and 86, respectively. TAVR CKD-LG had a higher percentage of in-hospital mortality (2.0% vs 1.4%, p=0.04) compared to TAVR CKD-HG. TAVR CKD-LG had a lower percentage of AKI (16.7% vs 25.3%, p<0.001) and major bleeding (1.6% vs 2.2%, p=0.04) compared to TAVR CKD-HG. There was no significant difference between groups in cerebrovascular accidents (CVA), post-procedural stroke, sudden cardiac arrest (SCA), transfusion, cardiogenic shock (CS), and mechanical circulatory support (MCS). The median length of stay in TAVR CKD-LG and TAVR CKD-HG were 2 days and 3 days, and the median adjusted total charges for TAVR CKD-LG and TAVR CKD-HG were $197,978 and $198,821, respectively. Octogenarians with CKD stage I-III had a higher percentage of in-hospital mortality compared to CKD stage IV-V but were associated with a lower percentage of AKI and major bleeding. CVA, post-procedural stroke, SCA, transfusion, CS, and MCS showed no statistically significant difference.