Abstract
AbstractHypothalamic stimulation in cats was found to produce an increase of the contractile force of the right ventricle as measured by a strain gauge arch. Concomitant tachycardia was generally observed. The responses were mediated both by cardiac sympathetic innervation and by catechols released from the adrenals. In some experiments the nervous mechanism dominated, in others the humoral factor. The hypothalamic area, the stimulation of which produced cardiac augmentation, appeared to correspond with“the sympathetic vasodilator area”. Muscle vasodilator as well as cardiac augmentative responses appeared concurrently.
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