Abstract
Smithies and Ford-Walker1 have suggested that the three haptoglobin phenotypes, namely, 1–1, 2–1, and 2–2, detected by starch gel electrophoresis are determined by a pair of allelic genes Hp 1 and Hp 2. The findings in the eighteen families reported by Smithies and Ford-Walker and also in 106 families reported later by Galatius-Jensen2 were fully consistent with this hypothesis. Furthermore, the frequencies of the phenotypes in different populations agree well with those expected assuming a Hardy-Weinberg equilibrium2–4.
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