Abstract
Anaphylactic transfusion reactions are rare occurring in approximately 1 in 50,000 red cell transfusions.1 One aetiology includes the development of antibodies against transfused IgA in patients with severe IgA deficiency. Diagnosis of IgA-related anaphylaxis involves the measurement of IgA levels and anti-IgA antibodies.2 Recently, the evidence underlying this entity and the causal relationship between laboratory tests and clinical manifestation has been questioned.3 We describe a case of a 50-year-old man with chronic anaemia with an infected enterocutaneous fistula.
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