Abstract
Atypical forms of Retinopathy of Prematurity; including aggressive posterior retinopathy of prematurity (APROP), that can be seen despite normal birth week and weight, exhibits atypical localization (Zone 3), rapid progression, independent progression without a stage, and cannot be controlled by treatment. APROP is a disease that requires careful examination and making critical decisions, which can progress rapidly if not treated and result in retinal detachment and blindness. APROP requires attention and experience in terms of recognition and treatment approach. So, anti-VEGF's are in the foreground in their treatment either alone or combined with argon laser photocoagulation.
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