Abstract
The attenuating influence of a pre-exposure of rats to a low concentration of ozone (O 3) for 7 days on a subsequent O 3 challenge was investigated. Effects of O 3 were quantified by measuring indicators of lung permeability and inflammation in bronchoalveolar lavage fluid. The results suggest that pre-exposure to relatively low levels of O 3 produces a diminished permeability response in lower airways of rats upon a following challenge with a higher level of O 3. Extrapolated to human exposure situations, these data suggest that health effect evaluation of repeated exposure periods of enhanced O 3 levels is rather complex and needs further investigation.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.