Abstract
A trial compliance, intraluminal pressure, transmural pressure and atrial stretch have been suggested as major stimuli for the production of atrial natriuretic peptide (ANP). These assumptions are mainly based on observations showing good correlations between pressures and ANP levels in heart failure due to heart diseases of various etiology. 1 Increasing pressure in the left and/or right atrium is followed by an increased stretch of the atrial wall in most heart diseases, except in cardiac tamponade and constrictive pericarditis. In an experiment with dogs, the rise of ANP during rapid volume expansion was decreased in the presence of cardiac tamponade, even if the right atrial pressure and the left end-diastolic pressure increased during the induced tamponade. 2 This indicates that pressure is not the only determinant, as has been presumed previously. To investigate this relation, we studied the relation between ANP and some important hemodynamic parameters in a patient during exercise before and after pericardiectomy.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
