Abstract
Background: Using endocardial spectral mapping in sinus rhythm we have found 2 kinds of atrial myocardium: the fibrillar with rightward-segmented spectrum - named AF-Nest - and the compact with leftward non-segmented spectrum. By inducing AF we have consistently observed very high-disorganized activation only in the AF-Nest [reactive resonant tissue] while the compact keeps well-organized rather regular activation [passive tissue]. These findings suggest that AF-Nests resonance plays a crucial role in AF physiopathology refeeding the arrhythmia.
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