Abstract

AbstractA direct asymmetric aldol reaction of aldehydes and acetone catalyzed by L‐Pro‐L‐Trp was performed in β‐caprolactamquaternary ammonium salt coordination ionic liquid media in the presence of N‐methylmorpholine (NMM) in high yield and with good enantioselectivity. The approach has the advantages of simple product isolation, and reusable catalyst and coordination ion liquids.

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