Abstract

Background Spirometry is widely regarded as a clinically invaluable measurement method that is of genuine recommend for the diagnosis and management of asthmatic patients. FEV-1 and FEV1/FVC are vastly perceived as asthma severity and control assessment indices, according to the present clinical guidelines. Since FEV-1 index is chiefly within normal ranges even in the most severe cases, the certain criteria for asthma diagnosis is immensely base upon it’s significant alteration after bronchodilator challenge test . FEF25-75% represents a well-established indicator of small airway disease now for decades, however, and It has been demonstrated that asthmatic patients do have remarkably lower FEF25-75%. Additionally FEF 2575% meaningful response to the bronchodilator challenge test is seen in some asthmatics that are healthy in terms of other prognostic parameters.

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