Abstract
No reports of serum parathyroid hormone (PTH) concentrations are available for Alaska Native populations. Design: Cross‐sectional study. Methods: PTH, serum 25(OH)D, dietary calcium and demographic variables were collected from 496 Alaska Natives of Western Alaska (43% males) ages 14‐92y residing in Southwestern Alaska. Results: Estimated calcium intake was 470 ± 341 and 376 ± 245 mg/d among men and women, respectively. Median PTH concentration (pmol/L) was 6.96 (2.4‐37.2), and 6.0 (2.4‐24.2) among men and 7.7 (2.6‐37.2) among women. In MLR models, predictors of PTH were 25(OH)D (P=0.02) and BMI (P=0.04) among men, and BMI (P<0.01), 25(OH)D (P=0.01) and an age x BMI interaction (P=0.02) among women.ConclusionBroadly low calcium intake was likely related to elevated PTH levels, but resulted in a weak calcium and PTH relationship. PTH concentrations were apparently moderated by 25(OH)D.
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