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Associations of Depressive Symptoms With Diabetes, Chronic Kidney Disease, and Physical Activity in Later Life.

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ObjectivesDiabetes-related chronic kidney disease (CKD) is a common and clinically consequential multimorbidity cluster in later life. This study examined the associations of depressive symptoms (PHQ-9) with diabetes, CKD, coexisting diabetes-CKD, and physical activity (PA).MethodsData came from the 2011-2023 National Health and Nutrition Examination Survey (N = 13,610 adults aged ≥50). Linear regression models were used to answer the research questions.ResultsIn models adjusting for sociodemographic factors and other chronic illnesses, diabetes (B = 0.38, SE = 0.14, p = .007) and coexisting diabetes-CKD (B = 0.58, SE = 0.17, p = .001) were associated with higher depressive symptoms, whereas meeting PA guidelines was associated with lower symptoms (B = -0.86, SE = 0.10, p < .001). The inverse association between PA and depressive symptoms was weaker among individuals with advanced CKD (p = .042).ConclusionsThese findings suggest that depressive symptoms and PA are closely linked in later life, highlighting the importance of supporting combined mental health and exercise interventions for older adults with complex chronic conditions.

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Impact of Physical Activity on Smoking, Sleep Disorders, and Depression Among U.S. Adults
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Smoking negatively impacts lung function and cardiovascular capacity, making physical activity (PA) more challenging and contributing to mental health issues. This study investigates the role of PA in mitigating the links between smoking, sleep disorders, and depressive symptoms in adults in the United States. Data from the 2017 to 2020 National Health and Nutrition Examination Survey (NHANES) were examined. Participants were categorized by PA adherence (≥ 900 metabolic equivalent tasks [METs]/week or not) and smoking status based on serum cotinine levels (< 0.05 for non-smokers, 0.05–15 for secondhand smokers, and > 15 ng/mL for active smokers). Relationships between sleep disorders, depressive symptoms, and PA/smoking were evaluated using survey logistic regression, with non-smokers meeting PA guidelines as the reference group. Stratified analyses were conducted by age group (21 - 39, 40 - 59, 60+ years). Active smokers not meeting PA guidelines had a significantly higher likelihood of moderate to severe depressive symptoms (odds ratio [OR] 2.21, 95% confidence interval [CI] = [1.34, 3.65]). Young active smokers meeting PA guidelines had greater odds of sleep disorders (OR = 2.86, 95% CI = [1.38, 5.93]). Among middle-aged adults, those not meeting PA guidelines exhibited elevated odds of sleep disorders (OR = 2.18, 95% CI = [1.33, 3.59]) and severe depressive symptoms (OR = 3.01, 95% CI = [1.11, 8.18]). For older adults, increased odds of depressive symptoms were observed (OR = 3.37, 95% CI = [1.22, 9.29]). These findings underscore the potential of PA to mitigate mental health risks among individuals exposed to smoking. Longitudinal research is required to confirm these associations and inform targeted interventions.

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Abstract P213: Examining Sociodemographic Disparities in Physical Activity and Diabetes: Preliminary Findings From 2007-2020 National Health and Nutrition Examination Survey
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Neighbourhood greenspace is associated with a slower decline in physical activity in older adults: A prospective cohort study
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Maintaining physical activity in later life is important for maintaining health and function. Activity outdoors, such as walking, jogging and cycling, may provide an accessible, sociable and practical solution, but maintaining outdoor mobility may be a challenge in later life. Providing green environments which are supportive of physical activity may facilitate this, yet research into how greenspace could be best used is inconclusive. This study evaluates the role of greenspace in protecting against decline in physical activity over time in older adults.Data from the European Prospective Investigation of Cancer Norfolk, UK, cohort 1993–2009 (N=15,672) was used. Linear regression modelling was used to examine the association between exposure to greenspace in the home neighbourhood and change in overall, recreational and outdoor physical activity measured in terms of metabolic equivalent cost (MET) in hours/week. Mediation analysis was conducted to assess if dog walking explained the relationship between greenspace and physical activity change. Models were adjusted for known and hypothesised confounders.People living in greener neighbourhoods experienced less of a decline in physical activity than those living in less green areas. Comparing change for those living in the greenest versus least green quartiles, participants showed a difference in overall physical activity of 4.21 MET hours/week (trend P=0.001), adjusted for baseline physical activity, age, sex, BMI, social class and marital status. This difference was 4.03 MET hours/week for recreational physical activity (trend P<0.001) and 1.28 MET hours/week for outdoor physical activity (trend P=0.007). Dog walking partially mediated the association between greenspace and physical activity change, by 22.6% for overall, 28.1% for recreational and 50.0% for outdoor physical activity (all P<0.001).Greenspace in the home neighbourhood may be protective against decline in physical activity among older people as they age. Dog walking is a potential mechanism in this relationship, and warrants further investigation as a way of maintaining physical activity in later life.

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Isotemporal substitution of sedentary behavior with physical activity and its influence on depressive symptoms among adults with overweight/obesity in the United States: A cross-sectional study
  • Aug 1, 2024
  • Heliyon
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Isotemporal substitution of sedentary behavior with physical activity and its influence on depressive symptoms among adults with overweight/obesity in the United States: A cross-sectional study

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