Abstract
The objective of the current study was to investigate the associations between lifetime classic psychedelic use and cardiometabolic diseases. Using data from the National Survey on Drug Use and Health (2005–2014), the present study examined the associations between lifetime classic psychedelic use and two types of cardiometabolic disease: heart disease and diabetes. Respondents who reported having tried a classic psychedelic at least once in their lifetime had lower odds of heart disease in the past year (adjusted odds ratio (aOR) = 0.77 (0.65–0.92), p = .006) and lower odds of diabetes in the past year (adjusted odds ratio (aOR) = 0.88 (0.78–0.99), p = .036). Classic psychedelic use might be beneficial for cardiometabolic health, but more research is needed to investigate potential causal pathways of classic psychedelics on cardiometabolic diseases.
Highlights
The objective of the current study was to investigate the associations between lifetime classic psychedelic use and cardiometabolic diseases
Lifetime classic psychedelic use was uniquely associated with a 23% lower odds of heart disease in the past year and a 12% lower odds of diabetes in the past year
Among the three main classes of classic psychedelics, neither lifetime tryptamine use, lifetime lysergic acid diethylamide (LSD) use, nor lifetime phenethylamine use were uniquely associated with heart disease or diabetes in the past year when simultaneously entered into the regression models, though the association between lifetime tryptamine use and diabetes in the past year approached conventional levels of significance
Summary
The objective of the current study was to investigate the associations between lifetime classic psychedelic use and cardiometabolic diseases. Using data from the National Survey on Drug Use and Health (2005–2014), the present study examined the associations between lifetime classic psychedelic use and two types of cardiometabolic disease: heart disease and diabetes. Previous research has found associations between lifetime classic psychedelic use and lower odds of being overweight or obese as well as lower odds of having hypertension in the past y ear[22,23], which are risk factors of cardiometabolic disease. Using pooled data from the National Survey on Drug Use and Health (2005–2014), the present study sought to investigate the associations between lifetime classic psychedelic use and two types of cardiometabolic disease: heart disease and diabetes. We hypothesized that lifetime classic psychedelic use would be associated with lower odds of heart disease in the past year as well as lower odds of diabetes in the past year
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