Association of Patient Race With Surgical Practice and Perioperative Morbidity After Myomectomy.

Impact of race and ethnicity on in vitro fertilization outcomes in infertile women with polycystic ovary syndrome in the United States

This study compared scores on the 40-item Narcissistic Personality Inventory for 14 Asian, 58 Caucasian, and 16 Hispanic American college women. Asian American women had significantly lower narcissism scores than Caucasian American women and also scored significantly lower on four of the seven component scales. Hispanic and Caucasian women had similar scores on narcissism. These results may be based on an ethnic response set and/or the influence of cultural values present in many traditional Asian cultures which are seemingly antithetical to narcissism and include modesty, respect for authority, and the valuing of relationship over individualism. The importance of including ethnic information in research is stressed.

In the United States, 5-year breast cancer survival is highest among Asian American women, followed by non-Hispanic white, Hispanic, and African American women. Breast cancer treatment disparities may play a role. We examined racial/ethnic differences in adjuvant hormonal therapy use among women aged 18-64 years, diagnosed with hormone receptor-positive breast cancer, using data collected by the Northern California Breast Cancer Family Registry (NC-BCFR), and explored changes in use over time. Odds ratios (OR) comparing self-reported ever-use by race/ethnicity (African American, Hispanic, non-Hispanic white vs. Asian American) were estimated using multivariable adjusted logistic regression. Analyses were stratified by recruitment phase (phase I, diagnosed January 1995-September 1998, phase II, diagnosed October 1998-April 2003) and genetic susceptibility, as cases with increased genetic susceptibility were oversampled. Among 1385 women (731 phase I, 654 phase II), no significant racial/ethnic differences in use were observed among phase I or phase II cases. However, among phase I cases with no susceptibility indicators, African American and non-Hispanic white women were less likely than Asian American women to use hormonal therapy (OR 0.20, 95% confidence interval [CI]0.06-0.60; OR 0.40, CI 0.17-0.94, respectively). No racial/ethnic differences in use were observed among women with 1+ susceptibility indicators from either recruitment phase. Racial/ethnic differences in adjuvant hormonal therapy use were limited to earlier diagnosis years (phase I) and were attenuated over time. Findings should be confirmed in other populations but indicate that in this population, treatment disparities between African American and Asian American women narrowed over time as adjuvant hormonal treatments became more commonly prescribed.

Leiomyoma May Explain Racial Differences in ART Outcome Between African American and Caucasian Women

The purpose of this study was to compare the daily inter- and intra-situational ambulatory blood pressure (BP) variation by ethnicity in women. The African-American (N = 82; Age = 39.7 + 8.9), Hispanic-American (N = 25; age = 37.5 + 9.4), Asian-American (N = 22; Age = 35.2 + 8.6), and European-American (N = 122; Age = 37.2+ 9.4) women in this study all worked in similar positions at two major medical centers in NYC. Each wore an ambulatory monitor during the course of one mid-week workday. Proportional BP changes from work or home to sleep, intra-situational BP variation (standard deviation [SD]) and mean situational BP levels were compared among the groups using ANOVA models. African-American and Asian-American women had significantly smaller proportional work-sleep systolic changes than either European- (P < 0.05) or Hispanic-American (P < 0.05) women, but the Asian-American women's changes tended to be smallest. The variability (SD) of diastolic BP at work was significantly greater among African- and Hispanic-American women compared to Asian- and European-American women (all P < 0.05). African-American women had greater sleep variability than European-American women (P < 0.05). Asian-American women had the highest level of sleep diastolic pressure (all comparisons P < 0.05). African-American and Asian-American women have an attenuated proportional BP decline from waking environments to sleep compared to European-American and Hispanic-American women. Asian-American nocturnal BP may be elevated relative to all other groups. Am. J. Hum. Biol. 28:932-935, 2016. © 2016Wiley Periodicals, Inc.

Reasons for persistent differences in breast cancer mortality rates among various racial and ethnic groups have been difficult to ascertain. To determine reasons for disparities in breast cancer outcomes across racial and ethnic groups. Prospective cohort. The authors pooled data from 7 mammography registries that participate in the National Cancer Institute-funded Breast Cancer Surveillance Consortium. Cancer diagnoses were ascertained through linkage with pathology databases; Surveillance, Epidemiology, and End Results programs; and state tumor registries. 1,010,515 women 40 years of age and older who had at least 1 mammogram between 1996 and 2002; 17,558 of these women had diagnosed breast cancer. Patterns of mammography and the probability of inadequate mammography screening were examined. The authors evaluated whether overall and advanced cancer rates were similar across racial and ethnic groups and whether these rates were affected by the use of mammography. African-American, Hispanic, Asian, and Native American women were more likely than white women to have received inadequate mammographic screening (relative risk, 1.2 [95% CI, 1.2 to 1.2], 1.3 [CI, 1.2 to 1.3], 1.4 [CI, 1.3 to 1.4], and 1.2 [CI, 1.1 to 1.2] respectively). African-American women were more likely than white, Asian, and Native American women to have large, advanced-stage, high-grade, and lymph node-positive tumors of the breast. The observed differences in advanced cancer rates between African American and white women were attenuated or eliminated after the cohort was stratified by screening history. Among women who were previously screened at intervals of 4 to 41 months, African-American women were no more likely to have large, advanced-stage tumors or lymph node involvement than white women with the same screening history. African-American women had higher rates of high-grade tumors than white women regardless of screening history. The lower rates of advanced cancer among Asian and Native American women persisted when the cohort was stratified by mammography history. Results are based on a cohort of women who had received mammographic evaluations. African-American women are less likely to receive adequate mammographic screening than white women, which may explain the higher prevalence of advanced breast tumors among African-American women. Tumor characteristics may also contribute to differences in cancer outcomes because African-American women have higher-grade tumors than white women regardless of screening. These results suggest that adherence to recommended mammography screening intervals may reduce breast cancer mortality rates.

Book Review| October 01 2022 Review: Nowhere to Run: Race, Gender, and Immigration in American Elections, by Christian Dyogi Phillips Nowhere to Run: Race, Gender, and Immigration in American Elections, by Christian Dyogi Phillips. New York. Oxford Press, 2021. 259 pages. $27.95 (paper). ISBN: 9780197538944 Tammy R. Greer Tammy R. Greer Clark Atlanta University Search for other works by this author on: This Site PubMed Google Scholar National Review of Black Politics (2022) 3 (3-4): 149–152. https://doi.org/10.1525/nrbp.2022.3.3-4.149 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn MailTo Tools Icon Tools Get Permissions Cite Icon Cite Search Site Citation Tammy R. Greer; Review: Nowhere to Run: Race, Gender, and Immigration in American Elections, by Christian Dyogi Phillips. National Review of Black Politics 1 October 2022; 3 (3-4): 149–152. doi: https://doi.org/10.1525/nrbp.2022.3.3-4.149 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentNational Review of Black Politics Search Nowhere to Run: Race, Gender, and Immigration in American Elections provides a qualitative and quantitative approach to understanding the social, political, and cultural positioning of Asian American women and Latinas as they seek elected office in the United States of America. Christian Dyogi Phillips, through personal interviews, the use of Gender, Race, and Communities in Elections (GRACE) datasets, as well as other gathered data, creates an understanding of how Asian American women and Latinas are able to navigate the nuances of (perceived) “traditional” social, cultural, and political norms to have the audacity to seek elected office. As Phillips notes, Nowhere to Run sets to “reveal how racialized and gendered institutions and processes simultaneously facilitate and constrain electoral opportunities” (4). Throughout, Phillips exposes how the white heterosexual Christian male view of who is to have political, social, and economic power in the United States continues to seep into the varying non-white... You do not currently have access to this content.

Socioeconomic and racial disparities among infertility patients seeking care

Breast cancer is the second leading cause of cancer death among American women. African American (AA) women are more likely to die from breast cancer than their Caucasian (CAU), Hispanic, Asian and Native American counterparts revealing a clear disparity between AA women and women of other races and ethnicities. Data collected by The American Cancer Society and others reveal that although AA women have a lower incidence of breast cancer than CAU women, AA women tend to have larger, more aggressive tumors, and have a lower 5-year survival rate. Importantly, AA women are more likely to die from breast cancer than any other ethnic group. While socio-economic, cultural and environmental factors are thought to contribute to these disparities, little is known as to whether biological differences exist between CAU and AA women with breast cancer. To determine the effects of bioactive dietary compounds, (–)-epigallocatechin-3-gallate (EGCG), found in green tea, and sulforaphane (SFN), found in broccoli, were administered to breast cancer cells derived from AA and CAU women. Our results reveal that the AA breast cancer cells showed dissimilarities in response to ECGG and SFN treatments when compared to CAU cell lines. Additionally, differential expression of several cancer related genes, including the human telomerase reverse transcriptase gene (hTERT), was seen in AA cells when compared to CAU cells. These data support the hypothesis that biological differences may contribute to the disparity among AA and CAU women with breast cancer and that these variations may be influenced by diet. Citation Information: Cancer Epidemiol Biomarkers Prev 2011;20(10 Suppl):B33.

Acne vulgaris is a common skin disease with a large quality of life impact, characterized by comedones, inflammatory lesions, secondary dyspigmentation and scarring. There are few large objective studies comparing acne epidemiology between racial and ethnic groups. This study aimed to define the prevalence and subtypes of acne in women of different racial groups from four ethnicities. The sample consisted of 2895 (384 African American, 520 Asian, 1295 Caucasian, 258 Hispanic and 438 Continental Indian) women ranging in age from 10 to 70 years. Photographs of subjects were graded for acne lesions, scars, dyspigmentation, and measurements taken of sebum excretion and pore size. Clinical acne was more prevalent in African American and Hispanic women (37%, 32% respectively) than in Continental Indian, Caucasian and Asian (23%, 24%, 30% respectively) women. All racial groups displayed equal prevalence of both subtypes of acne with the exception of Asians, for whom inflammatory acne was more prevalent than comedonal (20% vs. 10%) acne, and in Caucasians, for whom comedonal acne was more prevalent than inflammatory (14% vs. 10%) acne. Hyperpigmentation was more prevalent in African American and Hispanic (65%, 48% respectively) than in Asian, Continental Indian and Caucasian (18%, 10%, 25% respectively) women. Dyspigmentation and atrophic scarring were more common in African American and Hispanic women than in all other ethnicities. There was a negative correlation between pore size and skin lightness for all ethnicities. Sebum production was positively correlated with acne severity in African American, Asian and Hispanic women, and pore size was positively correlated with acne in African American, Asian and Continental Indian women, (for all above results, P<0.05). Only female participants were recruited. Data collection was restricted to four cities, with some ethnicities from single cities. Acne was evaluated only on the left side of the face and the two-dimensional nature of photography may not capture all skin surface changes. Acne prevalence and sequelae were more common in those with darker skin types, suggesting that acne is a more heterogeneous condition than previously described and highlight the importance of skin-colour tailored treatment.

Introduction: Black American women have the highest prevalence of obesity in the United States (US). Ethnic disparities in this risk factor for cardiovascular disease have been found; Afro-Caribbean women have lower rates of obesity compared with African American women. Contributing factors of the ethnic disparity in adult obesity have yet to be fully elucidated. However, the emergence of the ethnic disparity in adolescence suggests a potential role for childhood social determinants. Hypothesis: Childhood social determinants are hypothesized to explain the ethnic disparity in obesity between African American and Afro-Caribbean women in the United States. Methods: Multiple logistic regression models were used to examine childhood social factors and adult social, health and lifestyle risk factors that explain the ethnic disparity in obesity between African American (N = 2299) and Afro-Caribbean women (N = 978), 18 years and older, in the National Survey of American Life (2001-2003). Adult socioeconomic factors included marital status, education, occupation, home ownership and poverty status. Adult health and lifestyle risk covariates included hypertension, diabetes, menopausal status, smoking, alcohol use and physical activity. Childhood social factors included measures of parental education, receipt of public assistance prior to 18 years of age, and type of high school attended (private/parochial vs. public). Odds ratios (OR) of the association between ethnicity and adult obesity were estimated after adjusting age and adult socioeconomic measures, adult health and lifestyle measures and childhood social factors within the models. Results: The prevalence of obesity was 40.5% among African American women and 30.8% among Afro-Caribbean women. Afro-Caribbean women had 34% lower odds of obesity than African American women; age-adjusted OR = 0.66; 95%CI: (0.52, 0.82). Adjusting for age and adult socioeconomic factors slightly decreased the ethnic disparity; adjusted OR = 0.70; 95%CI: (0.53, 0.94). Adjusting for age and adult health and lifestyle factors decreased the disparity by 11%; adjusted OR = 0.73; 95%CI: (0.55, 0.97). Adjusting for age and childhood social factors eliminated the ethnic disparity; adjusted OR = 1.00; 95%CI: (0.82, 1.23). Conclusions: These findings suggest that childhood social factors are key contributors to the ethnic disparities in obesity between African American and Afro-Caribbean women in the US.

Background: Studies have documented lower rates of breast cancer survival for African American versus Caucasian women. Differences in compliance to adjuvant hormone therapy (AHT) may partially explain the survival disparity. The purpose of our study is to examine whether or not a difference in self-reported compliance to AHT exists between African American and Caucasian women and to describe which factors may impact this compliance. Methods: Women who were 2-10 years from diagnosis of estrogen receptor positive, non-metastatic breast cancer at the University of Chicago Hospital were asked to complete a voluntary mail-in survey. All information was self-reported. Compliance to AHT was defined as not missing more than 2 doses of therapy a month and completing 5 years of therapy (or still taking therapy if less than 5 years had passed between initiation of therapy and date of survey completion). Chi square tests and logistic regressions were performed to compare compliance rates by sociodemographic factors, reported perception of AHT importance, and self-perceived risk for breast cancer recurrence. Results: Among the 381 eligible patients, 217 (56.9%) completed the survey. Overall self-reported compliance rate to AHT was 78.5%. African American women (n = 66, 30.8%) reported lower compliance rates compared to Caucasian women (70.0% vs. 82.3%, P = 0.055). For both African American and Caucasian women, perceived importance of AHT (from not important to very important) was correlated with higher rates of reported compliance (OR = 10.65; 95% CI: 3.55-31.94). Patients who weighted their cancer doctor's opinion more when considering taking or stopping AHT were also more likely to report being compliant (OR = 1.99; 95% CI: 0.75-5.25), whereas patients who reported being very worried about side effects were less likely to report being compliant (OR = 0.34; 95% CI: 0.10-1.13). Perceived risk of breast cancer recurrence, however, was not associated with reported compliance. Conclusions: For both African American and Caucasian women, compliance to adjuvant hormone therapy was associated with greater perceived importance of therapy. This study suggests that educating our patients on the importance of hormone therapy may significantly impact their compliance. Citation Format: Christina H. Suh, Sumita Bhatta, Ningqi Hou, Zakiya N. Factors associated with compliance to adjuvant hormone therapy for African American and Caucasian women. [abstract]. In: Proceedings of the Fifth AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2012 Oct 27-30; San Diego, CA. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2012;21(10 Suppl):Abstract nr A31.

Background: To identify molecular factors associated with survival disparities, multiple studies have identified differentially expressed genes in tumors from African American women (AAW) compared to Caucasian women (CW), however, it is not clear whether these changes, such as increased expression of PHSPL, SOS1 and CRYBB2P1 in tumors from AAW, are clinically meaningful or represent population artifact. Gene expression data were thus evaluated in breast tumors with defined intrinsic subtypes, non-malignant breast tissue and blood from patients without breast disease. Methods: Gene expression data was generated using U133 2.0 microarrays for 184 breast tumors from AAW and CW matched by subtype, grade, age and presence of local or distant metastases, from 44 benign biopsy specimens, and from 143 peripheral blood samples from patients without current or past invasive breast disease. Principal component analysis (PCA) was performed using Partek Genomics Suite 6.6 and differentially expressed genes were detected using ANOVA with FDR&amp;lt;0.05, 2-fold difference defining significance. Results: When all tumors were analyzed together, only PSPHL, CRYBB2P1 and SOS1 were differentially expressed, each at significantly higher levels in tumors from AAW. When analyzed by subtype, PSPHL, CRYBB2P1, SOS1 and AMFR were expressed at higher levels in luminal A tumors (n=86) and SOS1 at higher levels in basal-like tumors (n=66) from AAW; no differentially expressed genes were detected in HER2-enriched (n=18) or luminal B (n=14) tumors. AMFR, CRYBB2P1, PSPHL and SOS1 were also expressed at significantly higher levels in both non-malignant breast tissue from AAW patients, and in blood specimens from disease-free AAW patients compared to non-malignant and blood specimens from CW. Conclusions: PCA demonstrates that molecular profiles of tumors from AAW are highly similar to those from CW; the few genes that are differentially expressed in tumor specimens are not associated with breast cancer as the same changes are also found in disease-free breast tissues as well as blood from patients without breast disease. Lack of meaningful genetic differences, even within specific tumor subtypes, suggests that disparity differences between AAW and CW with breast cancer are not attributable to molecular differences inherent to the tumors, but likely stem from other factors such as genetic predisposition to the development of basal-like tumors or altered provision of or response to treatment. Citation Format: Allyson L. Valente, Craig D. Shriver, Rachel E. Ellsworth. Gene expression profiling of breast tumors from African American and Caucasian women: Are molecular differences meaningful. [abstract]. In: Proceedings of the 105th Annual Meeting of the American Association for Cancer Research; 2014 Apr 5-9; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2014;74(19 Suppl):Abstract nr 3270. doi:10.1158/1538-7445.AM2014-3270

The Association of Genetic Polymorphisms in Sex Hormone Biosynthesis and Action with Insulin Sensitivity and Diabetes Mellitus in Women at Midlife

Psychosocial correlates of binge eating in Hispanic, African American, and Caucasian women presenting for bariatric surgery