Abstract
Association between Mean Platelet Volume-to-Lymphocyte Ratio and the Presence of Apical Mural Thrombus in Post-Myocardial Infarction Patients
Highlights
One of the major complications of myocardial infarction (MI) is left ventricular apical thrombus (AT) formation, which may favor blood stasis, increased coagulability and endothelial injury.[1]
Platelet-to-lymphocyte ratio (PLR) was defined as the absolute platelet count in the peripheral blood divided by the total lymphocyte count, and mean platelet volume-to-lymphocyte ratio (MPVLR) was calculated as the ratio of Mean platelet volume (MPV) to lymphocyte count
A total of 107 patients with anterior myocardial infarction were included in the study
Summary
One of the major complications of myocardial infarction (MI) is left ventricular apical thrombus (AT) formation, which may favor blood stasis, increased coagulability and endothelial injury.[1]. Platelet-to-lymphocyte ratio (PLR) has been suggested as an important and cheap prognostic factor in coronary heart disease.[6] It is an inflammatory marker derived from complete blood count and has been studied in various cancers,[7] chronic renal failures,[8] and coronary artery disease.[9]. Objective: We aimed to investigate the prognostic significance of the marker – mean platelet volume to lymphocyte ratio (MPVLR) in patients with AT. The receiver operating curve (ROC) analysis was used to show the optimal cut-off for MPVLR to predict AT. ROC analysis revealed moderate diagnostic value in predicting the presence of AT with a MPVLR cut-off > 4.75 (82.1% sensivity and 70.2% specifity (area under the curve=0.811, 95% confidence interval [CI]: 0.7310.891, p
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