Abstract
Background: Antiphospholipid antibodies (APL) are a heterogeneous group of autoantibodies that are detected in the serum of patients with a variety of conditions, including auto immune diseases, infections, lymphoproliferative disorders, thrombosis, thrombocytopenia and recurrent fetal loss or recurrent miscarriage. Aim: To determined association between IgM/IgG antiphospholipid and miscarriage among aborted women in Khartoum state. Method: A 90 blood samples were collected from 45 aborted women with history of abortion and they sated as case group and 45 healthy women as control. The blood samples were tested for IgM/IgG anti-phospholipid using ELISA technique. Results: The median of IgM anti-Phospholipids was increase significantly (P 0.000) among aborted women (median 26.8) than healthy control (median 7.4), and 80% of aborted women showed positive result and the median of IgG anti-Phospholipids was insignificantly (P 0.923) among aborted women (median 5.9) and healthy control (median 6.2), and 22.2% of aborted women showed positive result. IgM/IgG Anti-phospholipids shows insignificant increase with repeated abortion and age. Conclusion: There was a significant association between IgM antiphospholipid and miscarriage and insignificant of IgG APL.The concentration of IgM/IgG antiphospholipid is insignifiantly increased with age and recurrence of abortion.
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