Association between baseline parameters of the electrogastrogram and long-trem symptom improvement in gastroparetic patients treated with gastric electrical stimulation

Abstract

Previous studies have shown that gastric electrical stimulation (GES) with high frequency and low energy (Enterra device) is able to significantly inlprove gastroparetic symptoms l~he aim of this study was to investigate wlmther baseline parameters of the electrogastrogram (EGG) can predict symptom improvement in gastmparetic patients requiring GES, 30 patients (25F, mean age: 41 years) with refractory gastmparesls were included (19 diabetic, 7 idiopathic, and 4 posbsurgical!. AII patients received GES tbr more than one year as previously reported (AmJ Surg 2001 182: 676-681/. The study, consisted of: 1) baseline EGG recordings for 30 min in the fasting state arid for 2 hours afl.er a solid meal; 2) assessment of total symptom scores (TSS) of seventy and frequency of vomiting, nausea, early satiety, bloating, postprandial tullness, epigastric pain and burning, each graded using a 5-point scale (0 to 4) at baseline and after one year of GES. The running spectral analysis method was used to calculate the percentage of dysrhythmia (slow wave frequency > 4 cpm or 30% of recording time m 6 patients in both the fasting and fed state, 9 in the fasting and 4 in fed state only/. For all patients as a group, both a and 2) GES with high frequency and low energy does not correct gastric dysrhythmia. Theretbre in the future different electrical stimulation parameters will need to be developed to address gastric dysrhythmia patients with nausea and vomiting or gastroparesis