Abstract

The objective of this study is to evaluate the nutraceutical values of the leaf of Tapinanthus globiferus hosted by the neem tree. The phytochemical composition, antioxidant activities, antidiabetic properties, anti-inflammatory capabilities, and proximate composition of the Tapinanthus globiferus leaf powder (TLP) were examined. The results revealed the phytochemical profiles: phenol (501.51 mg/g), alkaloids (408.25 mg/g), saponins (7.16 mg/g), steroids (7.16 mg/g), flavonoids 933.79 mg/g) and tannins (86.53 mg/g); antioxidant assay results: Ferrous chelating activity (51.17%), hydroxyl radical inhibition (55.96%), ABTS (76.09%), DPPH (71.34%) and lipid oxidation inhibition (66.18%); antidiabetic assay results: the α-glucosidase inhibition (75.88%) and α-amylase inhibition (72.14 %); anti-inflammatory assays: antiproteinase activity (72.38%) and albumin denaturation inhibition (44.67%) of TLP. Tapinanthus globiferus leaf powder has nitrogen-free extract content of 36.09%, 18.47% crude protein, 13.27% moisture, 12.78% ash, 9.44% crude fibre, and 9.93% crude fat. These findings indicated that TLP had anti-inflammatory, anti-diabetic, and antioxidant properties.

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