Abstract

Background: Various studies have shown the association between dyslipidemia and cardio-vascular risk among patients of chronic renal disease but the association non-significant than patients with normal renal function. There was lack of evidence exists because patients with chronic renal disease were excluded from the major clinical studies where the association with that target dyslipidemia treatment was being evaluated
 Material & Methods: The present prospective study was conducted among the patients of Chronic Kidney Disease above 18 years of age and diagnosed on the basis of history, detailed clinical examination, and biochemical and sonological examination based upon National Kidney Foundation (NKF) criteria were enrolled into the study. Clearance from hospital ethics committee was taken before start of study. Written informed consent was taken from each study participant.
 Results: In the present study out of total study participants of chronic kidney disease 46% were in the 3rd stage of CKD, 38% were in the 4th stage of CKD and 16% were in the 5th stage of CKD. Out of total study participants of chronic kidney disease, 82% were managed by conservative treatment and 18% were being managed by hemodialysis. Out of total study participants of chronic kidney disease, 38% had normal lipid profile while 62% patients had dyslipidemia. We found statistically significant (p value < 0.05) association between dyslipidemia and hemodialysis and association between dyslipidemia and stages of chronic kidney disease was statistically non- significant (p value > 0.05).
 Conclusion: We concluded from the present study that dyslipidemia is significantly associated as an additional risk factor in patients of Chronic Kidney Disease. We found significant association of hemodialysis with abnormal lipid profile.
 Key words: Chronic kidney disease, dyslipidemia, hemodialysis.

Highlights

  • A study reported that more than 2 million people from all around the world were on treatment with dialysis or opt for a kidney transplant (1)

  • There was a lack of evidence exists because patients with chronic renal disease were excluded from the major clinical studies where the association with that target dyslipidemia treatment was being evaluated Material & Methods: The present prospective study was conducted among the patients of Chronic Kidney Disease above 18 years of age and diagnosed on the basis of history, detailed clinical examination, and biochemical and sonological examination based upon the National Kidney Foundation (NKF) criteria were enrolled into the study

  • In the present study out of total study participants of chronic kidney disease 46% were in the 3rd stage of CKD, 38% were in the 4th stage of CKD and 16% were in the 5th stage of CKD

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Summary

Introduction

A study reported that more than 2 million people from all around the world were on treatment with dialysis or opt for a kidney transplant (1). Various studies have shown the association between dyslipidemia and cardiovascular risk among patients of chronic renal disease but the association nonsignificant than patients with normal renal function (4). There was a lack of evidence that exists because patients with chronic renal disease were excluded from the major clinical studies where the association with that target dyslipidemia treatment was being evaluated (5). Various studies have shown the association between dyslipidemia and cardiovascular risk among patients of chronic renal disease but the association non-significant than patients with normal renal function. Out of total study participants of chronic kidney disease, 82% were managed by conservative treatment and 18% were being managed by hemodialysis. Out of the total study participants of chronic kidney disease, 38% had normal lipid profiles while 62% of patients had dyslipidemia.

Methods
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