Assessment of angle and anterior chamber changes after keratoplasty

Abstract

AbstractPurpose To quantify angle and anterior chamber changes after corneal transplantation using Visante OCT®Methods In this retrospective study, Visante OCT® examinations were performed in patients, awaiting keratoplasty, preoperatively(J‐1) and one month postoperatively(M+1). The anterior chamber depth(ACD), the angle‐opening distance at 500µm(AOD), the trabecular‐iris space area at 500µm(TISA) and the scleral spur angle(SPA) in the temporal and nasal quadrants were measured. Patients were classified based on their surgery: the surgery was penetrating keratoplasty(PK group), it was descemet’s stripping automated endothelial keratoplasty(DSAEK group). Preoperative and postoperative measurements were compared using signed rank test of Wilcoxon.Results Twenty patients were evaluated: fifteen(75%) in the DSAEK group, five(25%) in the PK. Mean anterior chamber depth width increased from 3,31mm(SD 0,69) to 3,35mm(SD 0,341) after PK(p=1) , and from 3,32mm(SD 0,666) to 3,44mm(SD 0,591)after DSAEK(p=0,719). In the temporal quadrant, after DSAEK, mean anterior chamber angle width increased from 0,281mm(SD 0,126) to 0,334mm(SD 0,100)(p=0,03) in the TISA and after PK ,mean anterior chamber angle width decreased from 0,273mm(SD 0,054)to 0,248mm(SD 0,118) (p=0,812). In the nasal quadrant, after DSAEK, mean anterior chamber angle width increased from 0,253mm(SD 0,089) to 0,285mm(SD 0,085)(p=0,207) in the TISA and after PK, from 0,269mm(SD 0,114)to 0,321mm (SD 0,069) (p=0,437).Conclusion The angle change significantly in the temporal quadrant after corneal transplantation. Larger study need to be perform to confirm the angle changes.