Abstract

Assessments of cognitive and verbal functions are widely used as screening tests to detect early dementia. This study developed an early dementia prediction model for Korean elderly based on random forest algorithm and compared its results and precision with those of logistic regression model and decision tree model. Subjects of the study were 418 elderly (135 males and 283 females) over the age of 60 in local communities. Outcome was defined as having dementia and explanatory variables included digit span forward, digit span backward, confrontational naming, Rey Complex Figure Test (RCFT) copy score, RCFT immediate recall, RCFT delayed recall, RCFT recognition true positive, RCFT recognition false positive, Seoul Verbal Learning Test (SVLT) immediate recall, SVLT delayed recall, SVLT recognition true positive, SVLT recognition false positive, Korean Color Word Stroop Test (K-CWST) color reading correct, and K-CWST color reading error. The Random Forests algorithm was used to develop prediction model and the result was compared with logistic regression model and decision tree based on chi-square automatic interaction detector (CHAID). As the result of the study, the tests with high level of predictive power in the detection of early dementia were verbal memory, visuospatial memory, naming, visuospatial functions, and executive functions. In addition, the random forests model was more accurate than logistic regression and CHIAD. In order to effectively detect early dementia, development of screening test programs is required which are composed of tests with high predictive power

Highlights

  • Dementia is rapidly increasing in line with worldwide aging

  • This study developed an early dementia prediction model for Korean seniors based on the random forest algorithm and compared its results and precision with those of a logistic regression model and decision tree model based on chi-square automatic interaction detection (CHAID)

  • The prediction model was developed by using random forest, and its accuracy was compared with those developed using a logistic regression model and a decision tree (Table 2)

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Summary

Introduction

Dementia is rapidly increasing in line with worldwide aging. As of 2013, the global dementia population was over 44 million, and it is expected to increase by more than three times to 135 million by 2050 [1]. The dementia population in Korea is increasing the fastest in the world. That is, it was 610,000 as of 2014, and it is predicted to increase two-fold every 20 years, multiplying by more than four times and reaching 2.71 million by 2050 [2]. Total supporting costs for dementia in Korea as of 2010 were estimated to be US$ 7.4 billion, and they are predicted to increase two-fold every 10 years and reach US$ 37.3 by 2050, exceeding 1.5% of GDP [4]. As the increase in the number of seniors with dementia leads to considerable losses, for the patients and for supporting families, local communities and the country as a whole

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