Abstract
Plant extracts have the potential to be safe alternatives to antibiotics that disrupt the gut flora. The aim of the present study was to assess the susceptibility of some gut bacteria to the extract from needles of Turkish pine (Pinus brutia Ten.) using microdilution method in an anaerobic chamber. Turkish pine needle extract promoted the growth of Bifidobacterium bifidum, Bifidobacterium infantis, and Lactobacillus acidophilus from gut commensals at 0.2-6.25 mg/mL, 0.4-6.25 mg/mL, and 0.4-1.6 mg/mL dose ranges, respectively (P
Highlights
The gut flora is a large and dynamic bacterial community that participates in normal physiological functions, and protects against pathogens by forming a defensive barrier and competing for available substrates (Ahn et al, 1998; Canny and McCormick, 2008)
Turkish pine needle extract promoted the growth of B. bifidum, B. infantis, and L. acidophilus from gut commensals at 0.2-6.25 mg/mL, 0.4-6.25 mg/mL, and 0.4-1.6 mg/mL dose ranges, respectively (P
The extract had a potential inhibitory activity on Bifidobacterium species starting from 12.5 mg/mL, on L. acidophilus starting from 6.25 mg/mL, and on L. casei starting from 3.13 mg/mL concentrations (P
Summary
The gut flora is a large and dynamic bacterial community that participates in normal physiological functions, and protects against pathogens by forming a defensive barrier and competing for available substrates (Ahn et al, 1998; Canny and McCormick, 2008). Balance great importance in terms of maintaining the gut health. Conventional antibiotics can prevent the growth of both commensal and pathogenic species and decrease diversity of the gut flora (Bäumler and Sperandio, 2016). Many studies have been focused on plant extracts as natural alternatives for antibiotics. Assessing the Susceptibility of Some Gut Bacteria to the Extract from Needles of Turkish Pine.
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