Abstract

Although primary angioplasty is the preferred treatment modality for acute myocardial infarction (MI), in centers without primary angioplasty (PA) capabilities, fibrinolytic therapy is still the recommended alternative. Combined fibrinolytic (CF) therapy has been shown to improve infarct-related artery (IRA) patency before PA and may improve safety of rescue angioplasty (RA). A randomized multicenter pilot study was conducted in the Asia-Pacific region to compare the safety and efficacy between primary angioplasty with adjunct abciximab vs combined fibrinolytic (alteplase and abciximab) therapy with or without rescue angioplasty for the treatment of AMI.

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