Abstract

BackgroundRampant caries is an advanced and severe dental disease that affects multiple teeth. This case describes the management of rampant caries in a young teenager suffering from chronic oral graft versus host disease after allogeneic bone marrow transplantation.Case presentationA 14-year-old Chinese boy suffering from β–thalassemia major was referred to the dental clinic for the management of rampant dental caries. An oral examination revealed pale conjunctiva, bruising of lips, and depapillation of tongue indicating an underlying condition of anemia. The poor oral condition due to topical and systemic immunosuppressants was seriously aggravated, and rampant caries developed rapidly, affecting all newly erupted, permanent teeth. The teeth were hypersensitive and halitosis was apparent. Strategies for oral health education and diet modification were given to the patient. Xylitol chewing gum was used to stimulate saliva flow to promote remineralization of teeth. Silver diamine fluoride was topically applied to arrest rampant caries and to relieve pain from hypersensitivity. Carious teeth with pulpal involvement were endodontically treated. Stainless steel crowns were provided on molars to restore chewing function, and polycarbonate crowns were placed on premolars, upper canines and incisors.ConclusionThis case report demonstrates success in treating a young teenager with severe rampant dental decay by contemporary caries control and preventive strategy.

Highlights

  • Rampant caries is an advanced and severe dental disease that affects multiple teeth

  • This paper describes the use of silver diamine fluoride (SDF) to treat rampant caries in a young teenager suffering from major β-thalassemia and subsequently developing oral graft versus host disease after allogeneic bone marrow transplantation

  • Case presentation A 14-year-old Chinese boy suffering from major β–thalassemia was referred to the dental clinic for treatment of rampant dental caries (Figure 1)

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Summary

Introduction

Rampant caries is an advanced and severe dental disease that affects multiple teeth. This case describes the management of rampant caries in a young teenager suffering from chronic oral graft versus host disease after allogeneic bone marrow transplantation.Case presentation: A 14-year-old Chinese boy suffering from β–thalassemia major was referred to the dental clinic for the management of rampant dental caries. Conclusion: This case report demonstrates success in treating a young teenager with severe rampant dental decay by contemporary caries control and preventive strategy. Rampant caries refers to advanced and severe dental disease that affects multiple teeth [3], and is typically seen in children with neglected oral care, frequent sugar or syrup medicine intake, individuals with decreased salivary flow, and those with poor oral hygiene and drug addiction.

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