Application value of extravascular lung water index and pulmonary vascular permeability index in patients with acute respiratory distress syndrome

Abstract

Objective To investigate the value of extravascular lung water index(EVLWI) and pulmonary vascular permeability index(PVPI) in the diagnosis and treatment of acute respiratory distress syndrome(ARDS). Methods From February 2015 to October 2016, selected 80 patients with ARDS in Danzhou Municipal People's Hospital, including 19 cases mild patients, 28 cases moderate cases and 33 cases severe cases.The patients’ EVLWI, PVPI, acute physiology and chronic health score system II (APACHE II) score, lung injury score (LIS) were detected. Results The score of APACHE II in severe group was 22.81(21.91, 25.40) points, significantly higher than that in mild group(19.81(18.12, 21.10) points) and moderate group(20.07(19.01, 22.02), P=0.002). The LIS, EVLWI and PVPI in Severe group were 2.01(1.83, 2.11) points, 17.01(14.82, 23.02) ml/kg and 3.82(3.01, 5.01), significantly higher than that in mild group(1.01(0.98) points, 1.7412.71(10.89, 13.67) ml/kg, 2.71(2.36, 2.94)) and moderate group(1.52(1.36, 1.91) points, 14.21(13.10, 16.60) ml/kg, 3.01(2.52, 3.03), P 0.05). Conclusion EVLWI and PVPI have certain application value in the diagnosis and treatment of ARDS, and it is related to the patient's condition and prognosis. Key words: Extravascular lung water index; Pulmonary vascular permeability index; Acute respiratory distress syndrome; Lung injury score; APACHE Ⅱ score