Abstract
Different attempts to increase retention of strong acids in ion exclusion chromatography are presented. A decrease of the dissociated forms of the sorbent functional groups which increases the retention of strong acids can be achieved either by decreasing the effective charge of the support, or by using a week exchanger as silica, instead of conventionally sulfonated resins. Another suggested way is the addition of ion pairing reagents to the mobile phase. All these attempts, which improve the separations, fit with a proposed theoretical model.
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