Abstract
Every company certainly wants a good product and lots of it in order to get a profit, where at this time the competition is very tight. Therefore, this research is motivated by the many reject problems in the primary packaging product process (filling). This research was carried out at a pharmaceutical company located in Bogor, Wanaherang by taking problems with infusion bottles in January -March 2022, researchers also used 3 comparisons of infusion bottle products in companies, includes: levofloxacin, metronidaol, paracetamol infusion where the number of rejects in January and the most rejects in paracetamol infusion products are 2,303 pcs for 3 months, therefore this study aims to reduce the existing rejects by using the DMAIC, KAIZEN, Six sigma, FMEA and 7tools methodswith the results of the study finding 3 critical to quality that covers: fiber, dirt, packaging. The researcher proposes to improve human resources using the KAIZEN 5Smethodand also scheduling operator training and machine maintenance checks every month so that during the production process minimize all obstacles.
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