Application of medicine-separated moxibustion combined with western medicine inpatients with renal edema

Objective To explore the application of tsusanli warming moxibustion in early rehabilitation in patients with cerebral infarction. Methods Totally 120 patients with cerebral infarction and stable vital signs treated in the Department of Neurology of the First People's Hospital of Huzhou from January 2018 to March 2019 were selected using convenient sampling and divided into control (n=60) and observation (n=60) groups according to the random number table. Patients in the control group received routine drug therapy and rehabilitation care, while patients in the observation group received warming moxibustion, routine drug therapy and rehabilitation care. Bathel Index (BI) , National Institute of Health Stroke Scale (NIHSS) and myodynamia were used to compare the effects of intervention. Results The total effective rate in the observation group was 91.3%, higher than 66.7% in the control group, and there was statistically significant difference between the two groups (P<0.05) . The number of patients with a BI ≥ 75 in the observation group were more than that in the control group 2 and 3 months after treatment, and there was statistically significant difference between the two groups (P<0.05) . The NIHSS score of the observation group was lower than that of the control group 2 and 3 months after treatment, and there was statistically significant difference between the two groups (P<0.05) . Conclusions Tsusanli warming moxibustion combined with integrated Chinese and Western medical methods in routine rehabilitation care show an obvious effect on the neurological function in patients with cerebral stroke during early rehabilitation, which can also improve their activities of daily living. Key words: Cerebral stroke; Tsusanli; Warming moxibustion

Objective To observe the curative effect and harmful reactions of lamivudine in the treatment of chronic hepatitis B. Methods A total of 121 cases patients with hepatitis B were at random divided into observation group of 69 cases and control group of 52 cases. The patients in the observation group oralIy took the laminvudine of 100 mg, one time a day. The patients in the control group were carried out the muscle injection of recombinant human interferon a-2b of 3,000,000 IU, one time a day. 2 weeks later,it was one time every other day. The vitamins and general hepatoprotectants were all additionally used in the observation group and control group and without the other anti-virus drugs added. After one-year's treatment,the curative effects ( serum ALT recovery rate, HBeAg negative conversion rate and serum HBV DNA negative conversion rate ) and harmful reactions in two groups were observed. The χ2 test for recovery rates and negative conversion rates in the control group and treatment group had been carried out. Results After one-year's treatment, the serum ALT recovery rate was 91.30% ( 63/69 ), HBeAg negative conversion rate was 52.17% ( 36/69 ) and serum HBV DNA negative conversion rate was 86.96% ( 60/69 ) in the observation group. In the control group, the serum ALT recovery rate was 42.31% ( 22/52 ), HBeAg negative conversion rate was 30.77% ( 16/52 ) and serum HBV DNA negative conversion rate was 48.08% ( 25/52 ). The differences had statistical significance (P＜0.05). The by-effect of lamivudine was lower than that of recombinant human interferon a-2b. Conclusions The lamivudine is an effective drug in the treatment of chronic hepatitis B. After one-year's successive treatment, the liver function becomes normal, viruses become negative and the sero-conversion is obvious. All of these are better than interferon. Therefore, it is valuable for clinical popularization. Key words: Laminvudine; Interferon; Chronic hepatitis B

Objective To investigate the effects of glutamine on intestinal functions of dogs following abdominal open injury coupled with seawater immersion.Methods Following open abdominal injury,30 adult dogs were randomly divided into 3 groups:the seawater immersion group(the control group),the routine treatment group(the conventional group)and the glutamine treatment group(the observation group),each consisting of 10 animals.Blood pressure,heart rate,respiration,abdominal circumference,bowel sound were monitored both before and after injury.Blood samples were collected for the detection of endotoxin,D-lactate,diamine oxidase(DAO),tumor necrosis factor alpha(TNF-a),interleukin-1(IL-1 and lactulose/mannitol(L/M)ratio.After 24 hours,small intestine tissues were taken for pathological detection and measurement of intestinal mucosal thickness and villous height.Results When compared with the conventional group,no statistically significant differences could be seen in mean artery pressure(MAP),heart rate,respiration,bowel sound and abdominal circumference for the observation group(P＞0.05).When compared with the conventional group and the observation group,significant differences could be noted in MAP and bowel sound for the control group(P＜0.05).And statistical significance could also be noted for heart rate,respiration and abdominal circumference at hours 12 and 24 respectively following injury(P＞0.05).Endotoxin:when compared with the conventional and observation groups,statistical significance could also be noted in endotoxin for the control group at hours 12 and 24 following injury(P＞0.05),and statistical significance could also be noticed for the observation group at hour 24,when compared with the control and conventional groups(P＞0.05).D-lactate:there were statistically significant differences for the conventional group,when comparisons were made between the 3 groups at hour 12 following injury(P＜0.05),however,no statistical significance could be noted between the observation group and the control group(P＞0.05).Statistical significance was observed for the conventional group,when compared with the control and observation groups(P＜0.05).And no statistical significance was noted,when a comparison was made between the observation and control groups(P＜0.05).DAO:when compared with the control and conventional groups,statistical significance could be noted for the observation group at hours 8 and 24 respectively following injury(P＜0.05).TNF-α:when compared with observation and conventional groups,there was statistical significance for the observation group at hours 12 and 24 respectively following injury(P＜0.05).IL-1:when compared with the control[(7.40±2.71)ng/L]and the conventional groups[(8.71±3.13)ng/L],statistical significance could be observed for the observation group at hour 12 following injury(P＜0.05),however no statistical significance could be noted,when a comparison was made between the observation and control groups.At hour 24 following injury,when compared with the control[(9.91±3.18)ng/L]and conventional groups[(10.12±2.25)ng/L],statistical significance could be noticed for the observation group(P＜0.05).Urine L/M ratio:statistical significance would be noticed for the observation group,when compared with the control and conventional groups(P＜0.05).Pathological results:only mild edema could be seen in the intestinal mucosal cells of the animals in the observation group under optical microscope,which was obviously lighter,when compared with the observation and control groups.And there were statistical differences in intestinal mucosal thickness and villous height,when compared with the conventional group(P＜0.05),however,no statistical differences could be noted,when a comparison was made between the control and conventional groups(P＞0.05).Conclusions Glutamine seems to have definitive therapeutic effects on intestinal dysfunction induced by abdominal injury coupled with seawater immersion. Key words: Seawater immersion; Open abdominal injury; Intestinal function; Glutamine; Therapeutic effect

Background:The continuous development of drug-resistant tuberculosis in recent years has brought new attention to tuberculosis. linezolid is usually used to treat infection in patients with pulmonary tuberculosis and pneumonia, for it has good effects on Mycobacterium tuberculosis, and has strong antibacterial activity on the drug-resistant strain. This study aims to investigate the effects of linezolid on serum procalcitonin (PCT), erythrocyte sedimentation rate (ESR), and C-reactive protein (CRP) in patients with pulmonary tuberculosis and pneumonia.Methods:Forty patients with pulmonary tuberculosis and pneumonia were divided into 2 groups: observation group (n = 20), patients treated with linezolid; control group (n = 20), patients treated with moxifloxacin. At 14 days, one month and 3 months of treatment, changes in serum PCT, ESR, CRP, and bacterial eradication rate (negative conversion rate) were compared between the 2 groups, and the incidence of adverse reactions was compared.Results:Serum PCT, ESR, and CRP in the 2 groups were significantly lower after 14 days of treatment than before treatment (P < .05), the decrease was more significant in the observation group, and the differences in ESR and CRP were statistically significant (t = 2.199, 2.494, P < .05). Furthermore, the negative conversion rate was higher in the observation group, but the difference was not statistically significant (P > .05). At one month of treatment, serum PCT, ESR, and CRP were lower in the observation group, and the difference in CRP was statistically significant (t = 3.274, P < .05). Furthermore, the negative conversion rate was slightly higher in the observation group, but the difference was not statistically significant (P > .05). At 3 months of treatment, differences in PCT, ESR, and CRP were not statistically significant, and the negative conversion rate was the same between the 2 groups. Furthermore, the incidence of adverse reactions was higher in the observation group, but all were mild, and the differences between these 2 groups were not statistically significant (P > .05).Conclusion:In the treatment of tuberculosis and pneumonia, linezolid can improve serum PCT, ESR, and CRP levels, and eradicate bacteria. However, adverse reactions should be strictly monitored to ensure its safety.

Objective To explore the characteristics of bronchial tuberculosis under a bronchoscope and analyze the clinical effect of local treatment of bronchial tuberculosis under a fiberoptic bronchoscope. Methods The clinical data of 92 cases of bronchial tuberculosis admitted to the Department of Respiratory and Critical Care Medicine of Leshan People′s Hospital in Sichuan Province in China from January 2016 to December 2017 were retrospectively analyzed. The patients were divided into an observation group (n=48) and a control group (n=44) according to the random number table method. The patients in both groups were treated with the standardized 3HRZE/9HR anti-tuberculosis oral drug therapy and atomization inhalation therapy, and the patients in the observation group was treated with local drug injection under a fiberoptic bronchoscope on this basis. The sputum acid-fast bacilli negative conversion rate at 1, 2, 3 and 6 months of treatment and the clinical efficacy at 6 months of treatment were compared between the two groups. The adverse reactions during the treatment were recorded and a long-term follow-up was conducted. Results The sputum negative conversion rate in the observation group was significantly higher than that in the control group at 3 and 6 months of treatment (P 0.05). In the observation group, 48 cases of bronchial tuberculosis were treated with anti-tuberculosis and bronchoscopy for 12 months and were all clinically cured. The clinical cure rate of 44 cases of bronchial tuberculosis in the control group was 77.27%. The difference of the long-term clinical cure rate between the two groups was statistically significant (P=0.000). Conclusion Local treatment for the patients with bronchial tuberculosis under a fiberoptic bronchoscope combined with conventional anti-tuberculosis drugs can effectively promote the sputum negative transformation, improve the clinical efficacy and shorten the treatment period. Key words: Fiberoptic bronchoscope; Bronchial tuberculosis; Isoniazid; Clinical analysis

Objective To explore the application of limbs and fingers movement combined with moxibustion in patients with PICC catheterization. Methods A total of 346 PICC catheterized patients treated from August 2014 to July 2017 were randomly divided into control group (173 cases) and observation group (173 cases) according to random number table method. The control group was given local hot-wet compression at 3-4 cm of puncture point after 24 h of catheterization, and the observation group was given preventive moxibustion with the direction of the punctured vein at the same site in the control group, and then was given limbs and fingers movement. The levels of serum monocyte chemoattractant protein-1 (MCP-1), tumor necrosis factor-α (TNF-α) and interleukin-8 (IL-8), hemorheological parameters [rate of high and low shear whole blood viscosity (RBV), rate of plasma specific viscosity (RPV), hematocrit (HCT)] and the incidence rates of mechanical phlebitis and venous thrombosis were compared between the two groups after intervention. Results The levels of MCP-1, TNF-α and IL-8 were (53.03±7.86), (85.93±10.72), (54.65±9.23) ng/L in the observation group, (60.27±8.45), (94.74±11.36), (63.08±10.07) ng/L in the control group, and there were significant differences (t =8.252, 7.419, 8.117, all P<0.05). The levels of high shear RBV, low shear RBV, RPV and HCT were (3.94±0.85) mPa·s, (6.55±1.22) mPa·s, (1.70±0.54) mPa·s and (43.71±4.82)% respectively in the observation group, (4.18±0.74) mPa·s, (6.97±1.25) mPa·s, (1.92±0.59) mPa·s and (45.13±4.65)% in the control group, and there were significant differences (t=2.789-3.618, P<0.05). The incidence rates of venous thrombosis and phlebitis were 1.16% (2/173) and 5.78% (10/173) respectively in the observation group, 5.78% (10/173) and 13.29% (23/173) in the control group, there were significant differences (χ2=4.230, 5.661, P<0.05). Conclusions Limbs and fingers movement combined with moxibustion can effectively improve the blood flow status, and reduce the occurrence of mechanical phlebitis and venous thrombosis in patients with PICC catheterization. Key words: PICC catheterization; Moxibustion; Mechanical phlebitis; Venous thrombosis; Limbs and fingers movement

Objective To investigate the clinical effects of acupuncture and moxibustion on promoting early motor dysfunction in patients with acute ischemic stroke. Methods A total of 130 acute ischemic stroke patients with early motor dysfunction were selected as the study subjects. The patients were divided into observation group and control group by random number table, with 65 cases in each group. The observation group received acupuncture rehabilitation. The control group was given traditional acupuncture and moxibustion. Fugl-Meyer motor function assessment score (FMA) and clinical neurological deficit score and evaluation criteria were compared. The improvement of limb motor function was compared between the two treatment methods. Results Compared with the degree of neurological deficit, the scores of improvement at two weeks and four weeks after treatment in the observation group were all better than those in the control group. The differences between the two groups were significant (P<0.05). FMA in the observation group and the control group were significantly improved compared with that before treatment, the difference was significant (P<0.05); the observation group improved better than the control group, the difference was significant (t=2.0152, P<0.05). Conclusions Acupuncture and Moxibustion can promote limb function and restore neurological deficits in patients with acute ischemic stroke associated with early motor dysfunction, which is more satisfactory than traditional acupuncture and rehabilitation therapy. Key words: Acupuncture rehabilitation generalization; Stroke; Early; Motor dysfunction

Objective To explore the effects of acupuncture combined with rehabilitation training on neural function, motor function and quality of life in patients with cerebral apoplexy. Methods From September 2015 to September 2017, ninety-four patients with stroke rehabilitation in Zhejiang Provincial Taizhou Hospital were selected and divided into observation group and control group according to random number table, with 47 cases in each group.The control group was treated with rehabilitation training, and the observation group was treated with acupuncture and moxibustion on the basis of the control group.The two groups were treated for 8 weeks.The changes of nerve function, motor function, balance function, daily living ability and quality of life before and after treatment were compared between the two groups. Results After 4 weeks and 8 weeks of treatment, the NIHSS score, FMA score, BBS score and BI index score of the two groups decreased compared with before treatment (observation group: t=21.481, 36.045, 10.726, 21.961, 14.040, 26.501, 25.827, 42.266; control group: t=12.011, 20.519, 5.527, 15.644, 7.201, 18.719, 15.836, 29.852, all P<0.05), and at 8 weeks after treatment, the NIHSS score, FMA score, BBS score and BI index score decreased compared with those at 4 weeks after treatment(observation group: t=17.791, 11.558, 12.486, 13.867; control group: t=10.352, 9.721, 11.028, 11.129, all P<0.05). The NIHSS scores of the observation group after 4 weeks and 8 weeks of treatment were lower than those of the control group[(8.94±1.02)points vs.(10.56±1.20)points, (5.61±0.78)points vs.(8.23±0.97)points, t=7.052, 14.431, all P<0.05]. The FMA scores of the observation group after 4 weeks and 8 weeks of treatment were lower than those of the control group[(18.54±3.24)points vs.(15.03±2.71)points, (27.39±4.13)points vs.(21.03±3.25)points, t=5.697, 8.297, all P<0.05]. The BBS scores of the observation group after 4 weeks and 8 weeks of treatment were lower than those of the control group[(35.27±3.67)points vs.(31.09±3.15)points, (45.86±4.51)points vs.(38.98±3.76)points, t=5.925, 8.033, all P<0.05]. The BI index scores in the observation group after 4 weeks and 8 weeks of treatment were lower than those in the control group[(63.26±5.68)points vs.(56.18±6.02)points, (79.21±5.47)points vs.(68.77±4.89)points, t=5.865, 9.755, all P<0.05]. Conclusion Acupuncture combined with rehabilitation training can improve the neurological function, motor function and quality of life of patients with cerebral apoplexy. Key words: Stroke; Acupuncture; Moxibustion; Rehabilitation

Objective To study the effect of moxibustion acupuncture and Chinese medicine external treatment for the severe knee osteoarthritis. Methods A total of 86 severe knee osteoarthritis patients were enrolled between December 2014 and December 2016, in Department of Integrated TCM & Western Medicine, Shijiazhuang first hospital. According to the enrolled sequency, patients were divided into observation group and control group, 43 in each group. The control group was treated with intra-articular injection of sodium hyaluronate of 2ml, and the observation group was treated with the combined acupuncture moxibustion and traditional Chinese medicine external treatment on the basis of the control group. Two groups were performed for 3 months of follow-up. The clinical effect, WOMAC values, VAS score and Lysholm scale, and the serum high sensitivity C reactive protein (hs-CRP), interleukin 1 (IL-1) and tumor necrosis factor a (TNF-a) changes before and after the treatment were observed and compared. Results The total effective rate of observation group was 93.0% (40/43), while control group total effective rate was 76.7% (33/43), and the differences between two groups was statistically significant (χ2=4.441, P=0.035). After treatment, the WOMAC joint stiffness scores (3.2 ± 1.2 vs. 4.8 ± 2.1, t=4.338), joint pain (4.2 ± 1.3 vs. 5.9 ± 1.7, t=4.903), daily activities (14.5 ± 2.8 vs. 18.7 ± 2.9, t=6.832) in observation group were significantly lower than those in the control group. The VAS score (2.5 ± 0.8 vs. 4.1 ± 1.2, t=7.275) in observation group was significantly lower than the control group, while the Lysholm score (74.2 ± 3.7 vs. 67.4 ± 3.9, t=8.295) was significantly higher than the control group (P<0.05). The serum hs-CRP (8.34 ± 2.24 mg/L vs. 13.67 ± 2.54 mg/L, t=10.321), IL-1 (0.85 ± 0.11 ng/L vs. 1.32 ± 0.42 ng/L, t=7.099), TNF-a (98.67 ± 15.74 ng/L vs. 178.44 ± 26.53 ng/L, t=16.955) in the observation group patients were significantly lower than those in the control group (P<0.05). Conclusions The acupuncture combined moxibustion and traditional Chinese medicine external treatment could treat severe knee osteoarthritis, improve the function of knee joint. Key words: Osteoarthritis, knee; Acupuncture; Direct moxibustion; Hot compress; Inflammatory cytokines

Objective To observe the clinical curative effect of traditional Chinese medicine hot compress combined with moxibustion in the treatment of urinary retention after orthopedic surgery. Methods 56 patients with postoperative uroschesis who underwent orthopedic surgerywere randomly divided into observation group and control group, and 28 cases in each group. All patients underwent pelvic muscle training, psychological counseling before surgery, and physical therapy with conventional methods such as induction of urination after surgery. The control group was treated with moxibustion Ququan acupoint, and the observation group was treated with Chinese herbal medicine hot compress on the basis of the above treatment. The patients in both two groups were treated for 28 days. At the end of the treatment, the clinical efficacy of the two groups was evaluated, also the time of first voiding after operation, the average effective time, urinary tract infection and urinary catheter replacement rate were compared. Results The total effective rate was 92.86% in the observation group and 78.57% in the control group.The effective rate in the observation group was higher than that in the control group (χ2=46.86, P 0.05). The urinary catheter replacement rate in the observation group was 7.14%, which was lower than 21.43% in the control group, the difference was statistical significance (χ2=2.33, P<0.05). Conclusion The clinical curative effect of traditional Chinese medicine hot compress combined with moxibustion in the treatment of urinary retention after orthopedic surgery is better than moxibustion alone. The time of first urination and the average time of effect are shortened, and the rate of urinary catheter replacement is reduced. It is effective, simply and conductively to clinical use. Key words: Drugs, Chinese herbal; Moxibustion; Urinary Retention

Objective To observe the clinical effect of small dose mifepristone combined with traditional Chinese medicine in the treatment of uterine gland disease. Methods 76 patients with uterine gland disease were selected, they were divided into the observation group(n=38) and control group(n=38) by using random number table method.The control group was treated with small dose of mifepristone, while the observation group was treated with small dose of mifepristone combined with traditional Chinese medicine.The clinical curative effects of the two groups were compared. Results After treatment, in the observation group, the pain degree of patients[(21.30±6.70)points], influence activity level[(17.30±12.00)points], activity loss[(1.80±0.70)spots] and grades of dysmenorrheal[(0.60±0.20)stages] were lower than those in the control group, the differences were statistically significant(t=5.645, 7.023, 4.932, 3.994, all P<0.05). After treatment, in the observation group, the uterine volume[(56.20±2.00)mm3], CA125 level [(32.10±2.10)U/mL] were lower than those of the control group (t=4.024, 4.413, all P<0.05). The incidence rate of adverse reaction of the observation group was 7.89%, which was significantly lower than that of the control group, the difference was statistically significant(χ2=14.757, P<0.05). The patients were followed up for 8 months, the recurrence rate of the observation group was 5.26%, which was lower than 26.32% of the control group, the difference was statistically significant (χ2=16.678, P=0.000). The menstrual recovery ratio less than or equal to three months of the control group was 81.58%, which was significantly higher than 63.16% of the control group, the difference was statistically significant (χ2=8.484, P=0.003). Conclusion In the treatment process of adenomyosis, the small dose of mifepristone combined with traditional Chinese medicine can alleviate the clinical symptoms, reduce the pain and reduce the volume of uterus, and it has less adverse reaction, safe and reliable, it is worth of clinical application. Key words: Uterine gland disease; Mifepristone; Traditional Chinese medicine; Curative effect

Objective To investigate the therapeutic effect of moxibustion on theⅡ andⅢ stage of pressure ulcer. Methods A total of 50 cases of pressure ulcer patients in the Geriatric Department of Hangzhou Red Cross Hospital from January 2016 to October 2017 were selected by convenience sampling method. According to the random number sequence table, 50 cases (total of 63 injured spots) were divided into control group and observation group, with 25 cases in each group. The control group received routine nursing care, moist healing treatment. The observation group was treated with moxibustion along meridians combined with strong points and wounds on the basis of routine treatment. Two groups of patients were compared with healing days and vascular endothelial growth factor (VEGF). Results The healing days in the observation group (21.43±2.75) days were less than that in the control group (25.15±3.23) days. The VEGF level in the observation group was (370.22±51.48) pg/ml, which was lower than that in the control group (401.62±54.23) pg/ml, and the differences were statistically significant (P<0.05). Conclusions Moxibustion along the meridian can effectively treat the Ⅱ and Ⅲ stages of pressure ulcer in elderly patients and obviously shorten the healing course. This traditional Chinese medicine should be popularized in clinical practice. Key words: Pressure ulcer; Heal; Moxibustion; Along the meridian

Objective To explore the clinical effect of nursing care by traditional Chinese medicine and western medicine for chronic pulmonary heart disease. Methods A total of 120 patients with chronic pulmonary heart disease treated at our hospital from October, 2014 to October, 2016 were randomly divided into an observation group (60 cases) and a control group (60 cases). The control group were given traditional western care and the observation group nursing care by traditional Chinese medicine and western medicine. The nursing effects of the two groups were compared. Results After nursing care by traditional Chinese medicine and western medicine, the nursing efficacy was 95.0% in the observation group and was 76.6% in the control group, with a statistical difference (P < 0.05). Conclusions Through nursing care by traditional Chinese medicine and western medicine for patients with chronic pulmonary heart disease, we can recognize the nursing key points, closely observe the disease changes, deal with the complications in time, and give the patients psychological nursing care and improve the patients' quality of life, so it is worth for reference. Key words: Chronic pulmonary heart disease; Integrated traditional Chinese and western medicine; Nursing care

Objective To explore the effects of moxibustion in improving the ventilatory function of patients with lung distension caused by deficiency of lung-spleen qi. Methods Totally 60 patients with lung distension caused by deficiency of lung-spleen qi were selected and divided into the observation group and the control group, with 30 cases in each group. Patients in the control group were given combined traditional Chinese medicine and western medicine treatment plus routine care, while patients in the observation group were treated with moxibustion with moxa sticks on the basis of treatment in the control group. The therapeutic effect between two groups were compared. Results After two continuous courses of treatment, in the pulmonary function test, the ratio of the forced expiratory volume in one second and forced vital capacity (FEV1/FVC) in the observation group was (73.13±1.23) %, and in the control group, it was (67.83±1.04) % (t=18.03, P<0.05) . The total effective rate in the observation group was 93.3%, and it was 83.3% in the control group (χ2=10.92, P<0.05) . Conclusions Moxibustion with moxa sticks could effectively improve the ventilation function of patients with lung distension caused by deficiency of lung-spleen qi. Key words: Moxibustion; Deficiency of lung-spleen qi; Lung distension; Ventilatory function

Objective To explore the effects of cluster nursing and Traditional Chinese Medicine (TCM) nursing in patients with severe acute pancreatitis. Methods Totally 76 patients with severe acute pancreatitis admitted in Yantai Zhifu Hospital from January 2017 to December 2018 were selected by convenient sampling and divided into the control group (n=38) and the observation group (n=38) according to the random number table. Patients in the control group received routine nursing, while patients in the observation group received cluster nursing and TCM nursing on this basis. The nursing effect, quality of life, related hospitalization indicators, and nursing satisfaction rate were observed and analyzed between the two groups. Results The total effective rate of nursing in the observation group was 89.47% (24/38) , which was higher than 63.15% (24/38) in the control group (P<0.05) ; the the MOS Item Short From Health Survey score in the observation group was higher than that in the control group, and the hospitalization costs and length of hospital stay in the observation group were less than those in the control group , nursing satisfaction rate in the observation group was higher than control group, the differences were statistically significant (P<0.05) . Conclusions The implementation of cluster nursing and TCM nursing for patients with severe acute pancreatitis can enhance the nursing effect, reduce the treatment cost, and improve the quality of life of patients. Key words: Pancreatitis; Quality of life; Cluster nursing; Traditional Chinese Medicine (TCM) nursing; Nursing effect; Satisfaction