Abstract
Objective To evaluate the effectiveness of lanthanum carbonate on chronic renal failure patients with hyperphosphatemia. Methods All patients were treated with normal kidney drugs, strict limits on food contain phosphorus, and were randomly divided into control group and treatment group. The treatment group was given lanthanum carbonate(750-2 250 mg, qd), the control group was given calcium carbonate(750-1 500 mg, qd). Results Compared with before treatment, the serum phosphorus levels in treatment group were significantly decreased after treatment(P<0.01). There was no obvious increase in serum calcium, and compared with control group on each time point, the serum phosphorus levels decreased more significantly in the treatment group after treatment; the blood PTH decreased more significantly in the treatment group after treatment, there were significant diffrences. Conclusions Lanthanum carbonate in the treatment of patients with chronic renal failure is more effective than calcium carbonate, and has less side effects. Key words: Lanthanum carbonate; Chronic renal failure; Hyperphosphatemia
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