Abstract
Flavonoids have a variety of physiological activities such as anti-free radicals, regulating hormone levels, antibacterial factors, and anti-cancer factors, which are widely present in edible and medicinal plants. Real-time detection of flavonoids is a key step in the quality control of diverse matrices closely related to social, economic, and health issues. Traditional detection methods are time-consuming and require expensive equipment and complicated working conditions. Therefore, electrochemical sensors with high sensitivity and fast detection speed have aroused extensive research interest. Carbon nanomaterials are preferred material in improving the performance of electrochemical sensing. In this paper, we review the progress of electrochemical sensors based on carbon nanomaterials including carbon nanotubes, graphene, carbon and graphene quantum dots, mesoporous carbon, and carbon black for detecting flavonoids in food and drug homologous substances in the last four years. In addition, we look forward to the prospects and challenges of this research field.
Highlights
With the development of the economy and the improvement of living standards, how to avoid or cure diseases through diet has become a fashionable way for people because of the side effects brought by drugs
In the Zhang’s study [7], they concluded that the co-treatment of quercetin and paclitaxel could significantly inhibit the proliferation of prostate cancer cells and increase their apoptosis, playing a beneficial therapeutic effect
We summarized the latest research progress of electrochemical sensors based on carbon nanomaterials including carbon nanotubes, graphene, carbon and graphene quantum dots, mesoporous carbon, and carbon black in detecting the bioactive components of flavonoids in food and drug homologous substances over the past four years
Summary
With the development of the economy and the improvement of living standards, how to avoid or cure diseases through diet has become a fashionable way for people because of the side effects brought by drugs. Flavonoids as abundant chemical components in food and medicine homologous substances have attracted widespread attention, owing to the important impact on its quality, function, and safety. Considering the great significance of identifying and quantifying of flavonoids in food and drug homologous substances to evaluate their quality and physiological functions, many analytical methods including high performance liquid chromatography (HPLC), ultraviolet spectroscopy (UV), and near-infrared spectroscopy (NIR) have been used [8]. These methods are characterized by expensive detection equipment, complicated and time-consuming procedures, and professional testing personnel [9,10]. This paper is focused on the development of electrochemical sensors based on carbon-based nanomaterials for determining flavonoids and the prospect of their quality and safety evaluation for food and drug homologous substances
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