Abstract
PRIMARY idiopathic aplastic anemia is manifested by a profound anemia associated with leukopenia, neutropenia and thrombopenia and later by hemorrhagic tendencies and hypocellular bone marrow. It is an acquired disease of unknown cause occurring infrequently in childhood. In contrast to this type of the disease is a similar clinical entity due to a known etiologic agent and termed symptomatic or secondary aplastic anemia. Ehrlich1in 1888 first described the occurrence of the condition under discussion and termed it aplastic anemia. Frank2in 1915 called the condition aleukia haemorrhagica. More recently Rhoads and Miller,3working on the effect of intensive therapy with liver extract, noted that certain cases of primary idiopathic aplastic anemia failed to respond to this treatment, and they added the term refractory anemias to apply to these instances. Thus, from Ehrlich to Rhoads, the correct term for this disease probably is primary idiopathic refractory aplastic
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
