APLA Syndrome in Pregnancy and its Outcome: A Case Report

Abstract

Antiphospholipid antibody syndrome is a heterogenous autoantibody mediated acquired thrombophilia, which is associated with severe life threatening complications during pregnancy and most important treatable cause of recurrent pregnancy loss. It was described in 1980s by E Nigel Harris and Aziz Gharavi. It is also called as Hughes syndrome. Clinician should have high index of suspicion of APLA in patient with history of recurrent abortions, Intra uterine death with unexplained cause. We are presenting a case of 27yr old G2A1 with 38 wks. of POG with history of pulmonary thromboembolism and pulmonary hypertension and deep vein thrombosis 2 years ago, she was diagnosed with APLA syndrome. Patient was followed up to term and she was asymptomatic throughout the pregnancy. She had full term normal delivery. Both mother and baby were stable and healthy. She was asymptomatic in her postpartum period