Abstract
The aim of this study was to prepare and characterize the calcium phosphates modified by different amount of Na+, Cu2+, Zn2+ and CO3 2−, and to investigate their activity in model solution (at pH = 7.45 and 37 °C) and antibacterial properties against Streptococcus pyogenes. According to XRD and FTIR spectroscopy data the apatite-related phases with partial substitution РО4 3− → СО3 2− (B-type) have been prepared. Presence of sodium and carbonate ions led to increase of solubility in model solution during the first 48 h, while modification with both Cu2+ and Zn2+ cations (up to 0.6 wt%) significantly improved antimicrobial properties against Streptococcus pyogenes.
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