Abstract
Adolescents and adults with ASD are at high risk for clinically significant symptoms of anxiety. Accurate symptom identification and differential diagnosis can be challenging due to the similarity of presentation of many anxiety and ASD symptoms. Although there are no gold-standard tools for assessment of anxiety in individuals with ASD, clinicians are encouraged to use a comprehensive multi-informant, multi-modal assessment approach. Research supports the use of cognitive behavioral therapy (CBT) for treatment of anxiety in ASD, particularly in high-functioning adolescents. ASD-specific treatment modifications may be helpful for achieving optimal treatment response. There is limited available evidence regarding the effectiveness or potential adverse effects of pharmacological treatments for anxiety in this population. Future research is needed to understand the etiology and mechanisms of anxiety in individuals with ASD and to examine short- and long-term efficacy and effectiveness of a range of treatments.
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