Abstract
Gastric content aspiration is a common side effect in the perioperative period. Consequently, a number of therapies have been developed to reduce the risk of aspiration. These include the administration of antacids, sodium citrate, antisecretory and prokinetic agents. Using pharmacodynamic efficacy data, commonly used dose regimens can be examined and recommendations for more effective protection formulated. Recommended regimens must distinguish between elective and emergency surgery.
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