Abstract
The essential oil of Hyptis suaveolens obtained by steam distillation was examined for its antioxidant and antimicrobial activities. The antioxidant activity was determined by means of the DPPH radical scavenging test and ABTS free radical decolorization assay. Results from both methods indicate that the antioxidant activity of H. suaveolens oil is time and concentration dependent. The antioxidant potential of H. suaveolens oil determined by the DPPH method expressed as IC50 was 3.72 mg/ml whereas the TEAC value determined by the ABTS assay was 65.02 µM/mg. The antimicrobial activity of the essential oil was assessed by the dilution and well diffusion methods. The results show that the antifungal potential of H. suaveolens oil is more pronounced than its antibacterial properties. Its fungal growth inhibitory activity was dose dependent with a MID value of 1:640. The 20% ethanolic solution of H. suaveolens oil had antifungal power similar to 6% boric acid, 2% benzoic acid, or 5% salicylic acid but higher than 4% phenol. The activity decreased when the oil was stored at high temperature (> 40°C). The results of GC-MS analysis indicated the changes in oil composition which led to the decrease in antifungal activity.
Highlights
YDOXH RI 7KH HWKDQROLF VROXWLRQ RI + + + +LQWRQ DJDU 7KH PL[WXUH ZDV WKHQ SRXUHG LQWR D VWHULOH SHWUL GLVK
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
Summary
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
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
