Abstract
This study aimed to evaluate the antioxidant and the antibacterial activities of the essential oils from three Moroccan species of the genus Lavandula (Lavandula dentata L., Lavandula mairei Humbert and, Lavandula stoechas L.). The antibacterial activities were evaluated by the minimal inhibitory concentration (MIC) and the disc diffusion method, against Gram-negative bacteria (Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae, Citrobacter koseri) and Gram-positive bacteria (Staphylococcus aureus). The antioxidant potential was evaluated using free radical Scavenging against 2,2-diphenyl-1-picrylhydrzyl (DPPH), ferric reducing activity power (FRAP), and total antioxidant capacity (TAC). The antibacterial activity of the essential oils showed higher activity against tested nosocomial bacteria especially against Klebsiella pneumoniae, Citrobacter koseri, and Staphylococcus aureus. The essential oil of Lavandula stoechas L. revealed the higher antioxidant activity as measured by DPPH (IC50 = 3,11 ± 0,13 mg/ml), FRAP (EC50 = 6,88 ± 0,8 mg/ml) and TAC (443,2 ± 38 mg AAE/g EO) assays. The essential oil of Moroccan Lavandula stoechas L. could have potential as antimicrobial compounds for the treatment of many infectious bacterial diseases, including multi-resistant bacterial strains of nosocomial origin.
Highlights
Nosocomial infections called healthcareassociated infections (HAI), are infections acquired during the time of receiving healthcare that was not already present at the moment of hospital admission [1]
The phytochemicals contained in essential oils of the three Lavandula species are estimated by more than 23 compounds for L. mairei [4] and 52 for booth L. dentata and L. stoechas [13]
This study is the first to evaluate the essential oil of L.mairei against some nosocomial bacteria (Escherichia coli, Klebsiella pneumonia, Acinetobacter baumannii and Citrobacter koseri)
Summary
Nosocomial infections called healthcareassociated infections (HAI), are infections acquired during the time of receiving healthcare that was not already present at the moment of hospital admission [1] These infections are commonly caused by bacteria that are resistant to several antibiotics and can lead to delayed recovery or even death [2]. Many studies have shown the potential of aromatic and medicinal plants as sources of compounds with antimicrobial activity [4,5]. One of these is the genus Lavandula that belongs to the Lamiaceae family and comprises more than 40 species [6]. The evaluation of essential oil against a microbe is an evaluation of all the existing compounds in this oil at the same time against this microbe (Houël et al 2015)
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
