Abstract
Nosocomial infection has been recognized as a crucial issue in the outcome of hospital care, with significant morbidity and mortality results. The primary routes of infection transmission to patients are the hands of health-care workers. This also evokes utilization of antiseptics for hand-washing purposes. Many of the antiseptics commercially available are sanitizers dependent on alcohol that have certain shortcomings or harmful effects. The regular use can cause dermal irritation. The aim of the present study was to formulate an herbal hand-wash using leave extracts of Terminalia catappa, fruits of Curcuma longa, and rinds of Garcinia indica. Using the Disc diffusion process, the antibiotic activity against skin pathogens was evaluated, and results were compared with commercial antimicrobial hand-wash. The results showed that the herbal hand-wash was more effective against Bacillus subtilis and Escherichia coli than the commercially available antiseptic hand-wash. The effectiveness of herbal hand-wash was analysed using the Glove Juice method, which revealed that herbal hand-wash is effective in reducing pathogenic microbes present on the hands better than commercial hand-wash. These plant extracts can therefore be used for formulating herbal hand-wash to prevent hand borne microbial infections.
Highlights
The most vulnerable part of body, skin epidermis, needs to be protected from being exposed to pathogenic bacteria
The Health Care Workers’ (HCWs) hands are the main routes of exposure of drug-resistant pathogens and severe infections [1]
In the present research Terminalia catappa, Curcuma longa, Garcinia indica were selected in formulation of herbal hand-wash
Summary
The most vulnerable part of body, skin epidermis, needs to be protected from being exposed to pathogenic bacteria. The Health Care Workers’ (HCWs) hands are the main routes of exposure of drug-resistant pathogens and severe infections [1]. This evokes utility of antiseptics for hand cleaning process. Many of the chemicals antiseptic are commercially available as sanitizers consisting alcohol, chlorhexidine and so on These hand-washes help to control contagious disease transmission associated with health care more effectively but they produce diverse effects on prolonged use. Their repeated application can lead to dermal irritation and pathogen resistance. Some researchers have shown that growing resistance in microbes towards chemical antiseptics has led to severe disease outbreaks
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
