ANTIMICROBIAL ACTIVITY OF BIOSYNTHESIZED SILVER NANOPARTICLES PREPARED FROM THE LEAF EXTRACT OF LANTANA CAMARA

Abstract

Lant ana camara commonly known as weed or red sage is found throughout India. It was reported to be use d in traditional medicine system for infectious diseases. The present study designed to evaluate antimicrobial activity of aqueous extract of Lantana camara a nd bio synthesized silver Nanoparticles from aqueous extract of Lantana camara . When the extract of the plant was treated with silver nitrate (1mM) solution , a yellowish brown color developed indicating the formation of silver Nanoparticles. The anti micro bial activity of biosynthesized silver Nanoparticles of the extract and aqueous extract of Lantana camara was investigated against two gram positive and two gram negative human pathogenic bacteria and fungi by using disc diffusion method. The biosynthesiz ed silver Nanoparticles showed promising anti bacterial activity at 300µg/ml concentration compared with aqueous extract of Lantana camara . Similarly the silver Nanoparticles at the same level of concentration also exhibited significant antifungal activity against Candida albicans and Aspergillus niger. Conclusion: The results indicate that the biosynthesized s ilver Nanoparticles from Lantana camara have better antimicrobial activity than with that of aqueous extract of Lantana camara and almost equal antim icrobial activity when compared with the standard.